| Type | Description |
|---|---|
| Definition | macrophage expressed 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-11-26 00:38:00 | these data provide the evidence that membrane-bound and secretory isoforms of perforin-2 are present in human macrophages and may play important roles in immune defense | 28705375 |
| 2016-07-02 10:52:00 | Collectively, these studies further underscore the biological significance of Perforin-2 and elucidate critical molecular events that culminate in Perforin-2-dependent killing of both intracellular and extracellular, cell-adherent bacteria. | 26418746 |
| 2016-02-13 11:13:00 | the impact of Perforin-2/macrophage-expressed protein 1 from the earliest multicellular organisms to modern vertebrates, as well as review the development of other membrane attack complexes of complement and Perforin domain member proteins | 26307549 |
| 2013-10-30 08:33:00 | Knockdown of perforin-2 in macrophages did not alter the invasion of host cells but did result in chlamydial growth that closely mirrored that detected in HeLa cells. | 23753625 |
| Type | IDs |
|---|---|
| Synonymous | MPG1, MPS1, Mpg-1 |
| Gene |
UniProtKB-ID:
MPEG1_HUMAN
UniprotKB:
Q2M385
UniParc:
UPI0000049D9F
EMBL:
BC112230,
BC104997,
CH471076,
AK074166
Ensembl:
ENSG00000197629
KO:
hsa:219972
|
| Nucleutide sequences |
EMBL-CDS:
BAB84992.1,
AAI12231.1,
AAI04998.1,
EAW73839.1
Ensembl_TRS:
ENST00000361050
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000354335
RefSeq:
NP_001034485.1
|
| Others |
UniRef100:
UniRef100_Q2M385
UniRef90:
UniRef90_Q2M385
UniRef50:
UniRef50_A1L314
UniGene:
Hs.744920
CCDS:
CCDS41650.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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