| Type | Description |
|---|---|
| Definition | tryptophan hydroxylase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:08:00 | Investigating the complex interplay between genotype and high-fat-diet feeding in the lactating mammary gland using the Tph1 and Ldlr knockout models. | 33427054 |
| 2020-11-21 13:18:00 | Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity. | 32160524 |
| 2020-04-25 12:59:00 | Mast cell Tph1 promotes obesity and insulin resistance. | 31974364 |
| 2019-04-20 10:49:00 | Overexpression of tryptophan hydroxylase-1 (TPH-1), an enzyme involved in 5-methoxytryptophan synthesis, reduces renal injury by attenuating renal inflammation and fibrosis, whereas TPH-1 deficiency exacerbates renal injury and fibrosis by activating NF-kappaB and inhibiting Nrf2 pathways. | 30931940 |
| 2018-12-22 10:45:00 | Both gut-specific Tph1 knockout mice and liver-specific Htr2a knockout mice are resistant to high fat diet-induced hepatic steatosis, without affecting systemic energy homeostasis. | 30446669 |
| Type | IDs |
|---|---|
| Synonymous | Tph |
| Gene |
UniProtKB-ID:
TPH1_MOUSE,
Q3TZH2_MOUSE,
Q3UK52_MOUSE,
Q9JHZ8_MOUSE
UniprotKB:
P17532,
Q3TZH2,
Q3UK52,
Q9JHZ8
UniParc:
UPI00001F4AF5,
UPI00000E6CA0,
UPI0000026EAE
EMBL:
AC090122,
AK146171,
AF273257,
BC072582,
AK157858,
J04758,
AK146134
Ensembl:
ENSMUSG00000040046
KO:
mmu:21990
|
| Nucleutide sequences |
EMBL-CDS:
AAA63401.1,
AAH72582.1,
BAE34236.1,
BAE26950.1,
BAE26925.1,
AAF86975.1
Ensembl_TRS:
ENSMUST00000049298,
ENSMUST00000107669,
ENSMUST00000168335
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000103296,
ENSMUSP00000037752,
ENSMUSP00000128107
RefSeq:
XP_011249148.1,
XP_036008805.1,
NP_033440.1,
NP_001129556.1,
NP_001263301.1
|
| Others |
UniRef100:
UniRef100_Q3TZH2,
UniRef100_Q9JHZ8,
UniRef100_P17532
UniRef90:
UniRef90_P17752,
UniRef90_Q9JHZ8,
UniRef90_Q3TZH2
UniRef50:
UniRef50_E9PR49,
UniRef50_P17752,
UniRef50_Q3TZH2
UniGene:
Mm.248684,
Mm.398047
CCDS:
CCDS21280.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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