| Type | Description |
|---|---|
| Definition | rhotekin 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:09:00 | CircRNA hsa_circRNA_104348 promotes hepatocellular carcinoma progression through modulating miR-187-3p/RTKN2 axis and activating Wnt/beta-catenin pathway. | 33311442 |
| 2020-04-04 12:22:00 | These findings indicate that miR-181 functions as a tumor suppressor and plays a substantial role in inhibiting the tumorigenesis and reversing the metastasis of ovarian cancer through RTKN2-NF-kappaB signaling pathway in vitro | 30309296 |
| 2019-07-20 10:28:00 | hese results suggested that RTKN2 is involved in the progression of human osteosarcoma, and may be a potential therapeutic target. | 30389712 |
| 2018-08-25 11:14:00 | mutations in Pakistani patients with dilated cardiomyopathy rs375563861 (C2orf40), rs143187236 (MYOM3), and rs564181443 (RTKN2) have 3 fold or higher allele frequency in South Asians than in the global populations | 29886034 |
| 2017-04-08 11:10:00 | RTKN2 was upregulated in human bladder cancer tissues and cell lines. Silencing of RTKN2 inhibited proliferation and invasion, and induced cell apoptosis. In addition, knockdown of RTKN2 arrested the cell cycle at the G1 phase via inhibition of the expression of cell cycle-associated proteins. | 27082503 |
| Type | IDs |
|---|---|
| Synonymous | PLEKHK1, bA531F24.1 |
| Gene |
UniProtKB-ID:
RTKN2_HUMAN
UniprotKB:
Q8IZC4
UniParc:
UPI00015E0FBA,
UPI00000372DA,
UPI000007413A
EMBL:
CH471083,
AL607150,
AY150309,
BC048002,
BC142725,
CR749217,
BC025765,
AC024597,
BC141821,
AK096671
Ensembl:
ENSG00000182010
KO:
hsa:219790
|
| Nucleutide sequences |
EMBL-CDS:
AAI41822.1,
EAW54232.1,
BAC04837.1,
AAH25765.1,
AAN71738.1,
AAI42726.1,
CAH18074.1
Ensembl_TRS:
ENST00000373789,
ENST00000395260
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362894,
ENSP00000378678
RefSeq:
XP_011537758.1,
NP_001269870.1,
XP_016871332.1,
XP_011537762.1,
NP_660350.2,
XP_016871333.1,
XP_011537759.1
|
| Others |
UniRef100:
UniRef100_Q8IZC4
UniRef90:
UniRef90_Q8IZC4
UniRef50:
UniRef50_Q8IZC4
UniGene:
Hs.58559
CCDS:
CCDS73140.1,
CCDS7263.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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