| Type | Description |
|---|---|
| Definition | topoisomerase (DNA) III beta |
| Date | Results | Publications |
|---|---|---|
| 2020-08-29 12:49:00 | Topoisomerase 3beta knockout mice show transcriptional and behavioural impairments associated with neurogenesis and synaptic plasticity. | 32561719 |
| 2013-11-16 11:09:00 | This study indicated a role for TOP3beta in mRNA metabolism and suggest that it is involved in neurodevelopmental disorders. | 23912948 |
| 2010-01-21 00:00:00 | DNA topoisomerase III beta has a role in infertility and aneuploidy | 12591952 |
| 2010-01-21 00:00:00 | suggest an unanticipated role for Top3beta beyond DNA repair in the activation of cellular responses to DNA damage | 18367668 |
| 2010-01-21 00:00:00 | Chromosomal abnormalities in top3beta(-/-) mice might lead to a persistent increase in apoptotic cells, which might in turn lead to the progression of autoimmunity | 17517607 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
TOP3B_MOUSE,
Q3UJF5_MOUSE
UniprotKB:
Q9Z321,
Q3UJF5
UniParc:
UPI0000001A8F
EMBL:
AB013603,
AK144709,
BC031723,
AK146475
Ensembl:
ENSMUSG00000022779
KO:
mmu:21976
|
| Nucleutide sequences |
EMBL-CDS:
AAH31723.1,
BAA34227.1,
BAE26026.1,
BAE27200.1
Ensembl_TRS:
ENSMUST00000232581,
ENSMUST00000023465
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000156132,
ENSMUSP00000023465
RefSeq:
XP_006522060.1,
XP_006522057.1,
NP_035754.1,
XP_006522058.1,
XP_036015767.1,
XP_036015766.1,
XP_030104903.1,
NP_001313505.1,
XP_030104905.1,
XP_006522055.1,
XP_006522054.1,
XP_017172426.1,
XP_030104904.1
|
| Others |
UniRef100:
UniRef100_Q9Z321
UniRef90:
UniRef90_Q9Z321
UniRef50:
UniRef50_O95985
UniGene:
Mm.326089
CCDS:
CCDS27990.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员