| Type | Description |
|---|---|
| Definition | FAU ubiquitin like and ribosomal protein S30 fusion |
| Date | Results | Publications |
|---|---|---|
| 2018-12-01 11:38:00 | FAU knockdown increased the plasma membrane targeting and function of F508del-CFTR, but not of wild-type CFTR. Investigation into the mechanism of action revealed a preferential physical interaction of FAU with mutant CFTR, leading to its degradation. | 29158263 |
| 2018-09-22 10:17:00 | The FAU rs769440 G allele had higher frequencies in patients with recurrent pregnancy loss. | 29084471 |
| 2014-11-07 17:48:00 | The C-terminal portion of the encoded protein displays antimicrobial activity against B. megaterium. | 12860195 |
| 2011-09-17 10:15:00 | In 293T/17 cells, Bcl-G knockdown also attenuates UV-induced apoptosis, so that Bcl-G may constitute a common factor in the pathways by which both FAU and UV-irradiation induce apoptosis | 21550398 |
| 2010-03-01 11:04:00 | siRNA-mediated downregulation of either Fau or Bcl-G expression inhibited apoptosis, and the inhibition produced by combining the two siRNAs was consistent with control of Bcl-G by Fau. | 19671159 |
| Type | IDs |
|---|---|
| Synonymous | FAU1, Fub1, Fubi, MNSFbeta, RPS30, S30, asr1 |
| Gene |
UniProtKB-ID:
UBIM_HUMAN
UniprotKB:
P35544
UniParc:
UPI00001379B3
EMBL:
AY398663,
AP003068,
X65921,
BC033877,
CR541974,
AK026639,
X65923
Ensembl:
ENSG00000149806
KO:
hsa:2197
|
| Nucleutide sequences |
EMBL-CDS:
CAA46714.1,
CAG46772.1,
AAQ87877.1,
BAB15515.1,
AAH33877.1,
CAA46716.1
Ensembl_TRS:
ENST00000529639,
ENST00000527548,
ENST00000531743
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000434440,
ENSP00000431822,
ENSP00000435370
RefSeq:
NP_001988.1
|
| Others |
UniRef100:
UniRef100_P35544
UniRef90:
UniRef90_P35544
UniRef50:
UniRef50_P35544
UniGene:
Hs.387208
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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