| Type | Description |
|---|---|
| Definition | transition protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-11-24 11:34:00 | Tnp1, Tekt1, and Plzf have essential roles in spermatogenesis and can be expressed during organ culture of testis; with this system, genes can be induced only at the molecular level and not beyond meiosis. | 29397043 |
| 2010-01-21 00:00:00 | TPs are required for normal chromatin condensation, for reducing the number of DNA breaks, and for preventing the formation of secondary defects in spermatozoa, eventual loss of genomic integrity, and sterility | 15083521 |
| 2010-01-21 00:00:00 | Epididymal sperm from the Tnp1 null genotypes demonstrated a general decrease in normal morphology, motility, chromatin condensation, and degree of protamine 2 processing with decreasing levels of transition proteins in mutant sperm. | 15189834 |
| 2010-01-21 00:00:00 | JHDM2A directly binds to and controls the expression of transition nuclear protein 1 (Tnp1) and protamine 1 (Prm1) genes, the products of which are required for packaging and condensation of sperm chromatin | 17943087 |
| 2010-01-21 00:00:00 | The elevated levels of the remaining TP in Tnp-mutant mice appeared to be a consequence of the prolonged nucleus retention, rather than increased synthesis. | 15163613 |
| Type | IDs |
|---|---|
| Synonymous | Stp-1, TP1, Tp-1 |
| Gene |
UniProtKB-ID:
STP1_MOUSE,
Q545L6_MOUSE
UniprotKB:
P10856,
Q545L6
UniParc:
UPI0000003EB1
EMBL:
X12521,
AK006495,
BC061170,
BC048494,
S80846
Ensembl:
ENSMUSG00000026182
KO:
mmu:21958
|
| Nucleutide sequences |
EMBL-CDS:
AAB21244.2,
AAH48494.1,
CAA31039.1,
AAH61170.1,
BAB24620.1
Ensembl_TRS:
ENSMUST00000027374
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000027374
RefSeq:
NP_033433.1
|
| Others |
UniRef100:
UniRef100_P10856
UniRef90:
UniRef90_P10856
UniRef50:
UniRef50_P09430
UniGene:
Mm.425024
CCDS:
CCDS35611.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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