| Type | Description |
|---|---|
| Definition | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:51:00 | Developmentally Programmed Tankyrase Activity Upregulates beta-Catenin and Licenses Progression of Embryonic Genome Activation. | 32442396 |
| 2020-10-24 13:54:00 | The deubiquitinating enzyme USP25 binds tankyrase and regulates trafficking of the facilitative glucose transporter GLUT4 in adipocytes. | 30886164 |
| 2019-01-19 11:39:00 | Study using Villin-creERT2;Tnks1-/-;Tnks2fl/fl mice, which harbored conventional Tnks1 deletion and inducible intestinal epithelium-specific Tnks2 knockout, shows that tankyrases regulate adult intestinal Lgr5+ stem cells and epithelium homeostasis by preventing cell death and promoting cell proliferation. | 30260955 |
| 2017-10-28 13:40:00 | Tank1/Tank2 inhibition aggravates kidney injury in the absence of CD2AP. | 27441654 |
| 2017-07-15 11:03:00 | These structural insights will be invaluable for the functional and biophysical characterization of TNKS1/2, including the role of TNKS oligomerization in protein poly(ADP-ribosyl)ation (PARylation) and PARylation-dependent ubiquitylation. | 27328430 |
| Type | IDs |
|---|---|
| Synonymous | 4930554K12Rik, AI662855, ARTD5, C86528, D130072O21Rik, TANK1, mTNKS1 |
| Gene |
UniProtKB-ID:
TNKS1_MOUSE
UniprotKB:
Q6PFX9
UniParc:
UPI00001CE5F0,
UPI00020B16FA
EMBL:
AC122458,
AK048860,
BC057370
Ensembl:
ENSMUSG00000031529
KO:
mmu:21951
|
| Nucleutide sequences |
EMBL-CDS:
AAH57370.1,
BAC33475.1
Ensembl_TRS:
ENSMUST00000033929
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000033929
RefSeq:
NP_780300.2
|
| Others |
UniRef100:
UniRef100_Q6PFX9
UniRef90:
UniRef90_O95271
UniRef50:
UniRef50_O95271
UniGene:
Mm.88364
CCDS:
CCDS22242.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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