| Type | Description |
|---|---|
| Definition | death effector domain-containing |
| Date | Results | Publications |
|---|---|---|
| 2011-02-05 11:00:00 | In uteri of Dedd-/- mice, development of the decidual zone and the surrounding edema after embryonic implantation was defective. This was accompanied by disintegration of implantation site structure, leading to embryonic death before placentation. | 21135503 |
| 2010-03-08 12:33:00 | DEDD plays an important role in maintenance of the Akt protein level, which in consequence supports the efficient incorporation of glucose into skeletal muscles and adipose tissues. | 20043882 |
| 2010-01-21 00:00:00 | The death effector domain-containing DEDD supports S6K1 activity via preventing Cdk1-dependent inhibitory phosphorylation. | 19106089 |
| 2010-01-21 00:00:00 | It regulates cell cycle and cell sizing. (review) | 19260450 |
| 2010-01-21 00:00:00 | DEDD acts as a novel inhibitor of the mitotic Cdk1/cyclin B1 complex and is an impeder of cell mitosis, and its absence critically influences cell and body size via modulation of rRNA synthesis | 17283331 |
| Type | IDs |
|---|---|
| Synonymous | CASP8IP1, DEFT, Dedpro1, FLDED1, KE05 |
| Gene |
UniProtKB-ID:
DEDD_MOUSE,
Q3U001_MOUSE
UniprotKB:
Q9Z1L3,
Q3U001
UniParc:
UPI00000019C6
EMBL:
AJ011386,
BC023668,
BC054445,
AF100342,
AK157342
Ensembl:
ENSMUSG00000013973
KO:
mmu:21945
|
| Nucleutide sequences |
EMBL-CDS:
AAH54445.1,
CAA09604.1,
AAD16415.1,
AAH23668.1,
BAE34055.1
Ensembl_TRS:
ENSMUST00000111299,
ENSMUST00000097467,
ENSMUST00000064950,
ENSMUST00000111300
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000068419,
ENSMUSP00000106931,
ENSMUSP00000106930,
ENSMUSP00000095075
RefSeq:
NP_001344480.1,
NP_001122081.1,
XP_006496802.1,
NP_001344482.1,
NP_001344479.1,
NP_035745.3,
NP_001344481.1,
XP_011237084.1,
XP_006496804.1
|
| Others |
UniRef100:
UniRef100_Q9Z1L3
UniRef90:
UniRef90_O75618
UniRef50:
UniRef50_O75618
UniGene:
Mm.270139
CCDS:
CCDS15490.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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