| Type | Description |
|---|---|
| Definition | tumor necrosis factor (ligand) superfamily, member 12 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:24:00 | Weak Inducer of Apoptosis (TWEAK) Enhances Activation of Inflammasome Signaling Axis through in Astrocytes: Implications for Parkinson's Disease. | 32759670 |
| 2020-09-26 13:04:00 | The TNF-like weak inducer of the apoptosis/fibroblast growth factor-inducible molecule 14 axis mediates histamine and platelet-activating factor-induced subcutaneous vascular leakage and anaphylactic shock. | 31679818 |
| 2020-07-25 11:41:00 | These results suggest that Fn14 deficiency protects mice from experimental atopic dermatitis, involving the attenuation of inflammatory responses and keratinocyte apoptosis. In the context of atopic dermatitis-like inflammation, TWEAK modulates keratinocytes via a TNFR1-mediated pathway. | 31515807 |
| 2019-11-02 13:23:00 | TWEAK/Fn14 mediates atrial-derived cardiomyocytes hypertrophy via signaling pathway. | 29971943 |
| 2019-09-14 11:09:00 | Confirming its critical role in TWEAK signaling, silencing TRAF3IP2 inhibited TWEAK autoregulation, TWEAKR upregulation, p38 MAPK, NF-kappaB and AP-1 activation, inflammatory cytokine expression, MMP and TIMP1 activation, collagen expression and secretion, and importantly, proliferation and migration | 29981796 |
| Type | IDs |
|---|---|
| Synonymous | Apo3l, Dr3l, Dr3lg, Tweak |
| Gene |
UniProtKB-ID:
TNF12_MOUSE,
Q5F2A0_MOUSE
UniprotKB:
O54907,
Q5F2A0
UniParc:
UPI00001B5398
EMBL:
AK020909,
AK170297,
AF030100
Ensembl:
ENSMUSG00000097328
KO:
mmu:21944
|
| Nucleutide sequences |
EMBL-CDS:
AAC53517.2,
BAB32249.1,
BAE41696.1
Ensembl_TRS:
ENSMUST00000181810
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000137972
RefSeq:
NP_035744.1
|
| Others |
UniRef100:
UniRef100_O54907
UniRef90:
UniRef90_O54907
UniRef50:
UniRef50_O54907
UniGene:
Mm.8983
CCDS:
CCDS24907.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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