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21938 Tnfrsf1b

21938

Tnfrsf1b

tumor necrosis factor receptor superfamily, member 1b

protein-coding

Mus musculus

基因描述

Type Description
Definition tumor necrosis factor receptor superfamily, member 1b

研究结论

Date Results Publications
2021-03-13 13:18:00 Oligodendrocytes modulate the immune-inflammatory response in EAE via TNFR2 signaling. 31785393
2021-03-06 13:34:00 Regulatory T Cells Expressing Receptor Type 2 Play a Major Role in CD4+ T-Cell Impairment During Sepsis. 32697326
2021-02-20 13:32:00 The Role of TNFR2 and DR3 in the In Vivo Expansion of Tregs in T Cell Depleting Transplantation Regimens. 32397343
2020-10-24 13:59:00 TNFR2 limits proinflammatory astrocyte functions during EAE induced by pathogenic DR2b-restricted T cells. 31852844
2020-04-11 11:48:00 TNFR2 maintains Foxp3 expression in Regulatory T cells by restricting DNA methylation at the Foxp3 promoter. In inflammation, loss of TNFR2 results in increased severity and chronicity of experimental arthritis, reduced total numbers of Regulatory T cells, reduced accumulation of Regulatory T cells in inflamed joints, and loss of inhibitory activity. 31597740

名称对应

Type IDs
Synonymous CD120b, TNF-R-II, TNF-R2, TNF-R75, TNF-alphaR2, TNFBR, TNFR80, TNFRII, TNFalpha-R2, Tnfr-1, Tnfr2, p75
Gene
UniProtKB-ID: TNR1B_MOUSE, Q545P4_MOUSE
UniprotKB: P25119, Q545P4
UniParc: UPI0000003E93
EMBL: AK004844, M59378, X87128, U39488, AK140332, Y14622, Y14619, AK153301, Y14621, BC141405, Y14623, Y14679, Y14620, AK004752, M60469
Ensembl: ENSMUSG00000028599
KO: mmu:21938
Nucleutide sequences
EMBL-CDS: CAA74969.1, CAA60618.1, AAA39752.1, AAA40463.1, AAA85021.1, BAB23533.1, BAE24341.1, BAE31883.1, BAB23610.1, AAI41406.1
Ensembl_TRS: ENSMUST00000030336
Protein sequencees
Ensembl_PRO: ENSMUSP00000030336
RefSeq: NP_035740.2, XP_036019858.1
Others
UniRef100: UniRef100_P25119
UniRef90: UniRef90_P25119
UniRef50: UniRef50_P25119
UniGene: Mm.235328
CCDS: CCDS18914.1

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