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21933 Tnfrsf10b

21933

Tnfrsf10b

tumor necrosis factor receptor superfamily, member 10b

protein-coding

Mus musculus

基因描述

Type Description
Definition tumor necrosis factor receptor superfamily, member 10b

研究结论

Date Results Publications
2020-08-13 17:12:00 DR5 does not promote apoptosis but acts through non-canonical MMP-EGFR-ERK1/2 signaling mechanisms to contribute to cardiomyocyte hypertrophy. 31473246
2020-02-01 13:47:00 Endoplasmic reticulum stress activated by hyperandrogenism in polycystic ovary syndrome promotes apoptosis of granulosa cells of antral follicles via induction of DR5. 30423122
2019-04-06 11:35:00 Targeting upregulated DR5 in alpha-SMA-expressing dermal myofibroblasts is a viable therapy for fibrosis in scleroderma. 30850660
2019-02-16 10:41:00 TRAIL/TRAIL-R interaction regulates CD4(+) T cell activation in autoimmune inflammation and directly suppresses T cell activation via inhibiting TCR signaling, suggesting that TRAIL-R serves as a novel immune checkpoint in T cell responses. 29403497
2017-11-25 13:33:00 Death receptor5 pathway and mitochondrial pathway, which are likely mediated by HIF-1alpha, contribute to hypoxia-induced spermatocyte apoptosis. 28444885

名称对应

Type IDs
Synonymous DR5, KILLER, Ly98, MK, TRAILR2, TRICK2A, TRICK2B, TRICKB
Gene
UniProtKB-ID: TR10B_MOUSE
UniprotKB: Q9QZM4
UniParc: UPI00000040BB
EMBL: AK050753, AB031082, BC065141, AK080069, AB031081, AK154993, AF176833
Ensembl: ENSMUSG00000022074
KO: mmu:21933
Nucleutide sequences
EMBL-CDS: BAE32980.1, AAH65141.1, BAC34404.1, AAD52656.1, BAA96463.1, BAA96462.1, BAC37821.1
Ensembl_TRS: ENSMUST00000022663
Protein sequencees
Ensembl_PRO: ENSMUSP00000022663
RefSeq: NP_064671.2, XP_036014468.1
Others
UniRef100: UniRef100_Q9QZM4
UniRef90: UniRef90_Q9QZM4
UniRef50: UniRef50_Q9QZM4
UniGene: Mm.193430
CCDS: CCDS27243.1

全选

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