| Type | Description |
|---|---|
| Definition | cell cycle activator and apoptosis regulator 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:27:00 | The protein Deleted in Breast Cancer-1 (DBC1) regulates vascular response and formation of aortic dissection during Angiotensin II infusion. | 32317757 |
| 2020-10-31 13:16:00 | A novel form of Deleted in breast cancer 1 (DBC1) lacking the N-terminal domain does not bind SIRT1 and is dynamically regulated in vivo. | 31591441 |
| 2019-06-01 11:46:00 | Insulin acutely regulates SIRT1 activity by triggering recruitment of PACS-2 and DBC1 to the SIRT1 N terminal region creating a regulatory hub. | 30415949 |
| 2016-03-26 10:59:00 | Dbc1 ablation increases Scd1 levels, causes obesity and insulin resistance. | 26074075 |
| 2016-01-02 11:04:00 | phosphorylation of DBC1 at its C terminus by IKKalpha facilitates its interaction with RelB and IKKalpha, indicating that DBC1-mediated suppression of alternative NF-kappaB is regulated by IKKalpha. | 26378077 |
| Type | IDs |
|---|---|
| Synonymous | 2610301G19Rik, Dbc1, mKIAA1967 |
| Gene |
UniProtKB-ID:
CCAR2_MOUSE
UniprotKB:
Q8VDP4
UniParc:
UPI00001D6F6A
EMBL:
AK031472,
BC021475,
BC038346,
BC025471,
AK050238
Ensembl:
ENSMUSG00000033712
KO:
mmu:219158
|
| Nucleutide sequences |
EMBL-CDS:
AAH25471.1,
BAC27420.1,
AAH21475.2,
AAH38346.1,
BAC34139.2
Ensembl_TRS:
ENSMUST00000035612
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000036924
RefSeq:
NP_666167.3,
XP_006518959.1,
XP_006518960.1
|
| Others |
UniRef100:
UniRef100_Q8VDP4
UniRef90:
UniRef90_Q8VDP4
UniRef50:
UniRef50_Q8VDP4
UniGene:
Mm.218284
CCDS:
CCDS49534.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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