| Type | Description |
|---|---|
| Definition | nuclear receptor subfamily 2, group E, member 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-13 11:57:00 | we conclude that TLX, by repressing Hes1 expression, counteracts quiescence and NOTCH activation in NSCs, thereby relieving NOTCH-mediated lateral inhibition of proliferation in basal progenitors. | 31178417 |
| 2020-05-09 13:52:00 | The results strongly suggest that TLX acts through E2F6 to regulate islet beta cell proliferation. | 30981507 |
| 2020-03-28 12:42:00 | A lack of TLX is implicated in deregulation of microglial phenotype and that consequently, the survival and function of newborn cells in the hippocampus is impaired. TLX may be an important target in understanding inflammatory-associated impairments in neurogenesis. | 28844503 |
| 2018-08-04 10:51:00 | Results demonstrate that social isolation stress during adolescence attenuates an exercise-induced increase in neurogenesis. This effect is most pronounced in the ventral hippocampus. TLX is necessary for the pro-neurogenic effects of exercise during adolescence. | 28972669 |
| 2017-11-18 11:36:00 | This study demonstrated that deletion of Tlx impairs motor, cognitive and anxiety-related behaviours during adolescence and adulthood in male and female mice with most effects occurring during adolescence rather than adulthood, independent of housing conditions. | 26970576 |
| Type | IDs |
|---|---|
| Synonymous | Mtl1, Mtll, TLL, Tlx, XTLL, fierce, frc, tailless |
| Gene |
UniProtKB-ID:
NR2E1_MOUSE,
Q78ZM1_MOUSE
UniprotKB:
Q64104,
Q78ZM1
UniParc:
UPI00000013A6
EMBL:
BC057104,
S77482,
AF520420,
AK132201
Ensembl:
ENSMUSG00000019803
KO:
mmu:21907
|
| Nucleutide sequences |
EMBL-CDS:
AAH57104.1,
AAB34090.1,
AAM74229.1,
BAE21029.1
Ensembl_TRS:
ENSMUST00000019938
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000019938
RefSeq:
XP_036011658.1,
NP_689415.1
|
| Others |
UniRef100:
UniRef100_Q64104
UniRef90:
UniRef90_Q64104
UniRef50:
UniRef50_Q64104
UniGene:
Mm.287100
CCDS:
CCDS23813.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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