| Type | Description |
|---|---|
| Definition | aldehyde dehydrogenase 1 family member B1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:17:00 | Role of aldehyde dehydrogenases, alcohol dehydrogenase 1B genotype, alcohol consumption, and their combination in breast cancer in East-Asian women. | 32300124 |
| 2020-05-02 11:25:00 | We identified AMI-5, a protein methyltransferase inhibitor, as an Aldh1b1 inducer and showed that it can maintain Aldh1b1 expression in embryonic pancreas explants. This led to a selective reduction in endocrine specification. This effect was due to a downregulation of Ngn3, and it was mediated through Aldh1b1 since the effect was abolished in Aldh1b1 null pancreata. | 30681750 |
| 2017-11-18 11:09:00 | These results suggest that ALDH1B1 is a novel human colorectal cancer biomarker | 28881356 |
| 2017-09-23 10:22:00 | The aims of this study were: (i) to use bioinformatic techniques to characterize the possible effects of selected variants in ALDH1B1 on protein structure and function; and, (ii) to genotype three missense and one stop-gain, protein-altering, non-synonymous single nucleotide polymorphisms in 1478 alcohol dependent cases and 1254 controls of matched British and Irish ancestry. | 28594837 |
| 2016-09-24 11:55:00 | ALDH1B1 is expressed at very high levels in human pancreatic cancer, and it contributes to proliferation in these tumor cells. | 26566217 |
| Type | IDs |
|---|---|
| Synonymous | ALDH5, ALDHX |
| Gene |
UniProtKB-ID:
AL1B1_HUMAN,
A0A384MTJ7_HUMAN
UniprotKB:
P30837,
A0A384MTJ7
UniParc:
UPI0000073000,
UPI0001E5EA3C
EMBL:
BT007418,
BC001619,
AL135785,
M63967,
GQ891318,
AK313344
Ensembl:
ENSG00000137124
KO:
hsa:219
|
| Nucleutide sequences |
EMBL-CDS:
AAP36086.1,
AAH01619.1,
BAG36147.1,
AAA96830.1,
ADO22180.1
Ensembl_TRS:
ENST00000377698
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000366927
RefSeq:
XP_011516104.1,
NP_000683.3
|
| Others |
UniRef100:
UniRef100_P30837,
UniRef100_A0A384MTJ7
UniRef90:
UniRef90_P30837
UniRef50:
UniRef50_P30837
UniGene:
Hs.436219,
Hs.743532
CCDS:
CCDS6615.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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