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218914 Wapl

218914

Wapl

WAPL cohesin release factor

protein-coding

Mus musculus

基因描述

Type Description
Definition WAPL cohesin release factor

研究结论

Date Results Publications
2021-02-13 13:27:00 WAPL maintains a cohesin loading cycle to preserve cell-type-specific distal gene regulation. 33318687
2021-01-02 12:50:00 Wapl releases Scc1-cohesin and regulates chromosome structure and segregation in mouse oocytes. 32328639
2020-09-05 13:59:00 Wapl repression by Pax5 promotes V gene recombination by Igh loop extrusion. 32612238
2017-12-30 10:51:00 The results demonstrate that the zygotic genome folds into loops and domains that critically depend on Scc1-cohesin and that are regulated in size and linear density by Wapl. 29217590
2017-11-26 01:38:00 NEK1 phosphorylates PP1gamma, leading to the dephosphorylation of WAPL, which, in turn, results in its retention on chromosome cores to promote loss of cohesion at the end of prophase I in mammals. 27760328

名称对应

Type IDs
Synonymous A530089A20Rik, BC037674, DIF-2, FOE, Wapal
Gene
UniProtKB-ID: WAPL_MOUSE, B7ZP47_MOUSE
UniprotKB: Q65Z40, B7ZP47
UniParc: UPI00003548FD, UPI00003548FE
EMBL: BC145625, AK129105, AC154276, BC139434, AB167349
Ensembl: ENSMUSG00000041408
KO: mmu:218914
Nucleutide sequences
EMBL-CDS: AAI39435.1, BAC97915.1, BAD44717.1, AAI45626.1
Ensembl_TRS: ENSMUST00000048263, ENSMUST00000169910, ENSMUST00000090027
Protein sequencees
Ensembl_PRO: ENSMUSP00000040232, ENSMUSP00000130547, ENSMUSP00000087481
RefSeq: NP_001288259.1, NP_001004436.2, XP_006518887.1
Others
UniRef100: UniRef100_B7ZP47, UniRef100_Q65Z40
UniRef90: UniRef90_Q65Z40, UniRef90_B7ZP47
UniRef50: UniRef50_Q65Z40
UniGene: Mm.27957
CCDS: CCDS36880.1

全选

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研究热度

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