| Type | Description |
|---|---|
| Definition | WAPL cohesin release factor |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:27:00 | WAPL maintains a cohesin loading cycle to preserve cell-type-specific distal gene regulation. | 33318687 |
| 2021-01-02 12:50:00 | Wapl releases Scc1-cohesin and regulates chromosome structure and segregation in mouse oocytes. | 32328639 |
| 2020-09-05 13:59:00 | Wapl repression by Pax5 promotes V gene recombination by Igh loop extrusion. | 32612238 |
| 2017-12-30 10:51:00 | The results demonstrate that the zygotic genome folds into loops and domains that critically depend on Scc1-cohesin and that are regulated in size and linear density by Wapl. | 29217590 |
| 2017-11-26 01:38:00 | NEK1 phosphorylates PP1gamma, leading to the dephosphorylation of WAPL, which, in turn, results in its retention on chromosome cores to promote loss of cohesion at the end of prophase I in mammals. | 27760328 |
| Type | IDs |
|---|---|
| Synonymous | A530089A20Rik, BC037674, DIF-2, FOE, Wapal |
| Gene |
UniProtKB-ID:
WAPL_MOUSE,
B7ZP47_MOUSE
UniprotKB:
Q65Z40,
B7ZP47
UniParc:
UPI00003548FD,
UPI00003548FE
EMBL:
BC145625,
AK129105,
AC154276,
BC139434,
AB167349
Ensembl:
ENSMUSG00000041408
KO:
mmu:218914
|
| Nucleutide sequences |
EMBL-CDS:
AAI39435.1,
BAC97915.1,
BAD44717.1,
AAI45626.1
Ensembl_TRS:
ENSMUST00000048263,
ENSMUST00000169910,
ENSMUST00000090027
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000040232,
ENSMUSP00000130547,
ENSMUSP00000087481
RefSeq:
NP_001288259.1,
NP_001004436.2,
XP_006518887.1
|
| Others |
UniRef100:
UniRef100_B7ZP47,
UniRef100_Q65Z40
UniRef90:
UniRef90_Q65Z40,
UniRef90_B7ZP47
UniRef50:
UniRef50_Q65Z40
UniGene:
Mm.27957
CCDS:
CCDS36880.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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