| Type | Description |
|---|---|
| Definition | thymidine kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2011-05-28 10:43:00 | The down-regulation of Tk1 activity unmasks Tk2 deficiency in Tk2-/- mice and correlates with the onset of mtDNA depletion in the brain and the heart. | 20940150 |
| 2010-10-04 11:27:00 | blood cells are less dependent on mitochondrial Tk2 compared with several other tissues; these cells can synthesize deoxyribonucleotides required for mtDNA replication by alternative pathways such as phosphorylation of thymidine by cytosolic Tk1 | 20440651 |
| 2010-01-21 00:00:00 | the small colony mutant phenotype in L5178Y lymphoma is not caused by deletion of both Trp53 and thymidine kinase 1 | 15215324 |
| 2010-01-21 00:00:00 | Alterations in Tk KO mice indicate that the pyrimidine nucleotide salvage pathway is indispensable in vivo. | 12559842 |
| 2010-01-21 00:00:00 | Mutations in the TK1 gene were studied in neonatal transgenic mice treated with AZT. | 15013700 |
| Type | IDs |
|---|---|
| Synonymous | D530002A18Rik, Tk-1, Tk1a, Tk1b |
| Gene |
UniProtKB-ID:
KITH_MOUSE
UniprotKB:
P04184
UniParc:
UPI000000418C
EMBL:
S57244,
M22581,
AK087988,
X60980,
M19438,
M11945,
M68489,
BC091758,
AK085188,
AK139244,
BC012215
Ensembl:
ENSMUSG00000025574
KO:
mmu:21877
|
| Nucleutide sequences |
EMBL-CDS:
AAB26001.1,
AAH91758.1,
AAA40450.1,
BAC40077.1,
CAA43296.1,
AAA40452.1,
BAE23931.1,
AAA40454.1,
AAA40451.1,
BAC39384.1,
AAH12215.1
Ensembl_TRS:
ENSMUST00000026661
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000026661
RefSeq:
NP_033413.2,
XP_006533212.1,
NP_001258658.1,
XP_036012517.1
|
| Others |
UniRef100:
UniRef100_P04184
UniRef90:
UniRef90_P04184
UniRef50:
UniRef50_P04184
UniGene:
Mm.2661
CCDS:
CCDS25692.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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