| Type | Description |
|---|---|
| Definition | NK2 homeobox 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:29:00 | Nkx2.1 downregulation is involved in brain abnormality induced by excess retinoic acid. | 32445470 |
| 2020-09-19 16:28:00 | The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development. | 32868762 |
| 2020-06-13 12:24:00 | studies led to the discovery of NKX2.1, a transcription factor that participates in the early morphogenesis of the developing hypothalamus, as a key player in establishing the early identity of melanocortin neurons by activating Pomc expression | 30886014 |
| 2020-06-13 10:24:00 | that midline epithelial cells (MECs) contribute to both tracheal and esophageal epithelium, and Isl1 is required for Nkx2.1 transcription in MECs | 31813798 |
| 2019-09-21 10:59:00 | Data demonstrate that Selenbp1 is a direct target of Nkx2-1, which inhibits lung adenocarcinoma growth in vivo. Selenbp1 is an important suppressor of lung tumor growth that functions in a positive feedback loop with Nkx2-1, and whose loss is associated with worse patient outcome. | 30002193 |
| Type | IDs |
|---|---|
| Synonymous | AV026640, Nkx2.1, T/EBP, Titf1, Ttf-1 |
| Gene |
UniProtKB-ID:
NKX21_MOUSE,
Q6PFE0_MOUSE
UniprotKB:
P50220,
Q6PFE0
UniParc:
UPI00001D61EB,
UPI0000020B7F
EMBL:
U19755,
BC080868,
BC057607
Ensembl:
ENSMUSG00000001496
KO:
mmu:21869
|
| Nucleutide sequences |
EMBL-CDS:
AAH80868.1,
AAA86100.1,
AAH57607.1
Ensembl_TRS:
ENSMUST00000178477,
ENSMUST00000001536
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000001536,
ENSMUSP00000136103
RefSeq:
XP_011242403.1,
XP_036013270.1,
XP_006515854.1,
NP_033411.3
|
| Others |
UniRef100:
UniRef100_Q6PFE0,
UniRef100_P50220
UniRef90:
UniRef90_B6DXM3,
UniRef90_P50220
UniRef50:
UniRef50_P50220
UniGene:
Mm.89972
CCDS:
CCDS25922.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员