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218630 Ccno

218630

Ccno

cyclin O

protein-coding

Mus musculus

基因描述

Type Description
Definition cyclin O

研究结论

Date Results Publications
2020-03-14 12:11:00 Data show defects in efferent duct multiciliogenesis underlie male infertility in GEMC1-, MCIDAS- or CCNO-deficient mice 30936178
2018-09-22 12:11:00 In air-exposed airway epithelia, induction of factors required for multiciliogenesis, including cyclin O (Ccno) and Multicilin (Mcidas), is AhR dependent, and air exposure induces AhR binding to the Ccno promoter. Submersion and hypoxic conditions impede AhR-dependent Ccno induction. 27554288
2015-06-27 10:16:00 Ccno-deficient multiciliated cells fail to sufficiently generate deuterosomes, and only reduced numbers of fully functional centrioles that undergo maturation to ciliary basal bodies are formed. 25712475
2013-10-26 13:57:00 We thus conclude that cyclin O, as an upstream regulator of MPF, plays an important role in oocyte meiotic resumption in mouse oocytes. 23515676
2012-09-29 10:45:00 Results show uracil-N-glycosylase (UNG) as a new molecular layer that shapes the specificity of activation-induced deaminase (AID)-induced mutations and may provide new insights into the role of AID in cancer development. 22665573

名称对应

Type IDs
Synonymous C86987, Ccnu, E130318K11, UDG2, Ung2
Gene
UniProtKB-ID: CCNO_MOUSE, B2RWG0_MOUSE
UniprotKB: P0C242, B2RWG0
UniParc: UPI00001C530F
EMBL: BC147759, AK086507, BC147766
Ensembl: ENSMUSG00000042417
KO: mmu:218630
Nucleutide sequences
EMBL-CDS: AAI47767.1, AAI47760.1
Ensembl_TRS: ENSMUST00000038404
Protein sequencees
Ensembl_PRO: ENSMUSP00000040083
RefSeq: NP_001074531.1
Others
UniRef100: UniRef100_P0C242
UniRef90: UniRef90_P0C242
UniRef50: UniRef50_P22674
UniGene: Mm.25457
CCDS: CCDS36782.1

全选

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