例如:"NBL1", "4681", "drought"
收藏
2186 BPTF

2186

BPTF

bromodomain PHD finger transcription factor

protein-coding

Homo sapiens

基因描述

Type Description
Definition bromodomain PHD finger transcription factor

研究结论

Date Results Publications
2019-11-23 10:38:00 data indicate that miR-3666 could play an essential role in cell proliferation, migration, and invasiveness by targeting BPTF and partly inhibiting the PI3K-AKT and EMT signaling pathways in human lung cancers 30481052
2019-08-10 11:02:00 Study identified a novel NSUN2 methylated lncRNA (NMR), which was significantly upregulated in esophageal squamous cell carcinoma (ESCC), functioned as a key regulator of ESCC tumor metastasis and drug resistance. NMR could directly bind to chromatin regulator BPTF, and potentially promote MMP3 and MMP10 expression by ERK1/2 pathway through recruiting BPTF to chromatin. 29763634
2019-08-03 10:20:00 High BPTF expression is associated with gastric cancer growth and invasion. 30922402
2019-03-23 10:20:00 our data provide functional evidence and mechanistic insights that BPTF drives HCC progression, including promoting tumor cell proliferation, sustaining CSC traits, and increasing tumor metastasis, by transcriptionally activating the expression of hTERT. 30419422
2019-02-02 10:47:00 High BPTF expression in glioma tissue specimens was significantly associated with WHO grade and tumor size. Survival analysis revealed that the BPTF highexpression group had poorer overall and progressionfree survival compared with the lowexpression group. 30542695

名称对应

Type IDs
Synonymous FAC1, FALZ, NEDDFL, NURF301
Gene
UniProtKB-ID: BPTF_HUMAN
UniprotKB: Q12830
UniParc: UPI0001838807, UPI00002263BF, UPI00002263BE
EMBL: U05237, AC134407, AC107377, BC067234, AB032251, AC006534, AY282495
Ensembl: ENSG00000171634
KO: hsa:2186
Nucleutide sequences
EMBL-CDS: AAH67234.1, BAA89208.1, AAA97522.1, AAP22284.1
Ensembl_TRS: ENST00000306378, ENST00000321892
Protein sequencees
Ensembl_PRO: ENSP00000315454, ENSP00000307208
RefSeq: NP_004450.3, XP_005257208.1, XP_011522825.1, XP_005257215.1, XP_024306415.1, XP_011522826.1, NP_872579.2, XP_016879843.1, XP_016879842.1, XP_024306414.1, XP_005257209.1, XP_011522827.1, XP_011522824.1, XP_005257218.1, XP_011522823.1, XP_005257210.1, XP_011522828.1, XP_005257216.1, XP_005257217.1, XP_005257214.1, XP_005257212.1, XP_005257207.1, XP_011522822.1, XP_005257211.1, XP_005257213.1
Others
UniRef100: UniRef100_Q12830
UniRef90: UniRef90_Q12830
UniRef50: UniRef50_Q12830
UniGene: Hs.444200
CCDS: CCDS11673.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员