| Type | Description |
|---|---|
| Definition | tissue inhibitor of metalloproteinase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:31:00 | TIMP-2 suppresses tumor growth and metastasis in murine model of triple-negative breast cancer. | 31621840 |
| 2019-10-05 10:35:00 | Current study elucidated the distinct nature of the inhibitory effect on IS as a result of overexpressed miR-410 whereby the conferral of neuroprotection was observed in oxidative stress-induced apoptosis post IS through the TIMP2-dependent repression of the MAPK pathway in mice. | 30240841 |
| 2019-04-20 12:40:00 | Glycosaminoglycan, CaG can strengthen ECM by increasing activity of TIMP-2 and adhesion activity on collagen known to inhibit changes of extracellular matrix, leading to tumor cell invasion and progression | 30611221 |
| 2017-07-01 12:33:00 | the protein expression levels of TIMP-2 and PBEF in cloned placentae, were examined. | 27855185 |
| 2016-12-17 10:44:00 | demonstrate that TIMP-2 plays a greater protective role than TIMP-1 during the pathogenesis of atherosclerosis | 26645981 |
| Type | IDs |
|---|---|
| Synonymous | D11Bwg1104e, Timp-2 |
| Gene |
UniProtKB-ID:
Q6PI17_MOUSE,
Q8BSJ3_MOUSE
UniprotKB:
Q6PI17,
Q8BSJ3
UniParc:
UPI00000EACB1,
UPI000000102A
EMBL:
AL591404,
AK032818,
BC049126
Ensembl:
ENSMUSG00000017466
KO:
mmu:21858
|
| Nucleutide sequences |
EMBL-CDS:
AAH49126.1,
BAC28038.1
Ensembl_TRS:
ENSMUST00000017610
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000017610
RefSeq:
NP_035724.2
|
| Others |
UniRef100:
UniRef100_Q8BSJ3,
UniRef100_P30121
UniRef90:
UniRef90_P30121
UniRef50:
UniRef50_P30121
UniGene:
Mm.206505
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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