| Type | Description |
|---|---|
| Definition | timeless circadian clock 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-28 12:56:00 | The mutation prevents TIM accumulation in the nucleus and has altered affinity for CRY2. | 31138685 |
| 2015-11-21 11:49:00 | The obtained results suggest that Tim is expressed in neuronal tissues in a spatiotemporally regulated manner and involved in developmental stage-specific neuronal functions. | 25448545 |
| 2013-09-21 11:41:00 | The Phosphorylation of timeless protein by Hck and Fyn induced Tim ubiquitylation on K48 and subsequent degradation, while c-Src and c-Yes led to K63-linked ubiquitylation and Tim accumulation within cells. | 23266470 |
| 2013-08-31 11:12:00 | Data indicate that knockdown of TIMELESS (TIM) in NIH3T3 and U2OS cells shortens the period by 1 hour and diminishes DNA damage-dependent phase advancing. | 23418588 |
| 2011-09-03 10:18:00 | A new function for Tim in the coordination of ES cell differentiation and in developmental apoptosis. | 21359199 |
| Type | IDs |
|---|---|
| Synonymous | C77407, Debt69, tim |
| Gene |
UniProtKB-ID:
TIM_MOUSE,
Q3U574_MOUSE
UniprotKB:
Q9R1X4,
Q3U574
UniParc:
UPI00004E195D,
UPI00000E831A,
UPI00004408DE,
UPI0000025B86,
UPI00001D3F90,
UPI00004E195C
EMBL:
BC052884,
BC026526,
BC058641,
AF126480,
AF098161,
BC064788,
AK153838,
BC082770,
AF071506,
AB015598,
AB019001
Ensembl:
ENSMUSG00000039994
KO:
mmu:21853
|
| Nucleutide sequences |
EMBL-CDS:
AAD24467.1,
AAH64788.1,
AAC79687.1,
AAH26526.1,
BAA36500.1,
AAH82770.1,
BAA76390.2,
AAC80010.1,
AAH58641.1,
AAH52884.1,
BAE32206.1
Ensembl_TRS:
ENSMUST00000105244,
ENSMUST00000055539,
ENSMUST00000105242,
ENSMUST00000105245
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000100876,
ENSMUSP00000100878,
ENSMUSP00000058021,
ENSMUSP00000100879
RefSeq:
NP_035719.1,
XP_006513646.1,
XP_006513643.1,
NP_001157553.1,
XP_006513644.1,
XP_030100909.1,
XP_006513645.1,
NP_001157552.1,
NP_001129554.1,
XP_030100910.1
|
| Others |
UniRef100:
UniRef100_Q9R1X4,
UniRef100_Q3U574
UniRef90:
UniRef90_Q9R1X4
UniRef50:
UniRef50_Q9UNS1
UniGene:
Mm.6458
CCDS:
CCDS48725.1,
CCDS24266.1,
CCDS48724.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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