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218518 Marveld2

218518

Marveld2

MARVEL (membrane-associating) domain containing 2

protein-coding

Mus musculus

基因描述

Type Description
Definition MARVEL (membrane-associating) domain containing 2

研究结论

Date Results Publications
2019-10-19 11:04:00 This study has shown that the Endolymphatic Sac in Tric-/- mice showed no changes in morphology or disruption in macromolecular barrier function. The effects of solute leakages in the ES of Tric-/- mice may be very limited and compensable, or that the ES epithelia may have other sealing system covering the lack of tricellulin. 30100545
2017-09-30 13:36:00 Findings suggest that both tricellular tight junctions proteins TRIC and LSR have crucial roles for the differentiated cochlear cell survival. 28767685
2016-08-27 12:45:00 Tricellulin is a specific redox sensor and sealing element at 3-cell contacts and may compensate as a redox mediator for occludin loss at 2-cell contacts in vivo and in vitro. 25919114
2015-01-31 11:36:00 GFP-tagged angulin-1/LSR, in which serine 288 was substituted by alanine, was observed to be dispersed to bicellular junctions, indicating that phosphorylation of Ser288 is crucial for the exclusive localization of angulin-1/LSR and tricellulin at tTJs. 24889144
2014-10-11 11:06:00 localization of angulin-1/LSR and tricellulin at tricellular contacts of brain and retinal endothelial cells in vivo 24212375

名称对应

Type IDs
Synonymous BC003296, MARVD2, Mrvldc2, Tric, Trica, Tricb, Tricc
Gene
UniProtKB-ID: MALD2_MOUSE, A1BQX3_MOUSE, E9Q1T5_MOUSE
UniprotKB: Q3UZP0, A1BQX3, E9Q1T5
UniParc: UPI0001C2BFA3, UPI00005AB9E2
EMBL: DQ682659, AC165159, BC049919, BC003296, DQ143929, AK133741, AB219935
Ensembl: ENSMUSG00000021636
KO: mmu:218518
Nucleutide sequences
EMBL-CDS: AAH49919.1, AAH03296.1, BAE54512.1, BAE21816.1, ABA18656.1, ABG89107.1
Ensembl_TRS: ENSMUST00000022137, ENSMUST00000168772, ENSMUST00000225754, ENSMUST00000163163
Protein sequencees
Ensembl_PRO: ENSMUSP00000153294, ENSMUSP00000126438, ENSMUSP00000022137, ENSMUSP00000129990
RefSeq: NP_848497.2, XP_006517668.1, NP_001033691.1
Others
UniRef100: UniRef100_Q3UZP0, UniRef100_E9Q1T5
UniRef90: UniRef90_E9Q1T5, UniRef90_Q3UZP0
UniRef50: UniRef50_E9Q1T5, UniRef50_Q8N4S9-3
UniGene: Mm.25300
CCDS: CCDS26732.1

全选

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研究热度

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