| Type | Description |
|---|---|
| Definition | protein tyrosine kinase 2 beta |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:20:00 | CD56 regulates human NK cell cytotoxicity through Pyk2. | 32510326 |
| 2020-12-19 13:39:00 | Pyk2 Regulates Human Papillomavirus Replication by Tyrosine Phosphorylation of the E2 Protein. | 32727877 |
| 2020-12-12 13:23:00 | The proline-rich tyrosine kinase Pyk2 modulates integrin-mediated neutrophil adhesion and reactive oxygen species generation. | 32693110 |
| 2020-10-24 14:06:00 | FAK and Pyk2 activity promote TNF-alpha and IL-1beta-mediated pro-inflammatory gene expression and vascular inflammation. | 31110200 |
| 2020-04-11 12:29:00 | These data suggests a FAK/PYK2 regulated pro-survival role of ERK5 in response to cell adhesion in MDA-MB 231 breast cancer cells. | 30952431 |
| Type | IDs |
|---|---|
| Synonymous | CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK |
| Gene |
UniProtKB-ID:
FAK2_HUMAN
UniprotKB:
Q14289
UniParc:
UPI000000D9EC,
UPI000002A95D
EMBL:
AF311103,
L49207,
BC036651,
U33284,
U43522,
CH471080,
BC042599,
S80542,
D45853
Ensembl:
ENSG00000120899
KO:
hsa:2185
|
| Nucleutide sequences |
EMBL-CDS:
AAB47217.1,
EAW63556.1,
AAH36651.1,
AAB35701.1,
EAW63555.1,
AAH42599.1,
EAW63553.1,
AAC50203.1,
AAC05330.1,
BAA08289.1
Ensembl_TRS:
ENST00000420218,
ENST00000397501,
ENST00000517339,
ENST00000346049
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000427931,
ENSP00000391995,
ENSP00000332816,
ENSP00000380638
RefSeq:
NP_775266.1,
XP_011542744.1,
XP_005273504.1,
XP_016868703.1,
XP_016868704.1,
NP_004094.3,
XP_016868705.1,
XP_005273505.1,
XP_011542743.1,
NP_775267.1,
NP_775268.1
|
| Others |
UniRef100:
UniRef100_Q14289
UniRef90:
UniRef90_Q14289
UniRef50:
UniRef50_Q14289
UniGene:
Hs.491322,
Hs.735450
CCDS:
CCDS6058.1,
CCDS6057.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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