| Type | Description |
|---|---|
| Definition | phosphodiesterase 8B |
| Date | Results | Publications |
|---|---|---|
| 2013-03-16 11:08:00 | Pde8b knockout mice demonstrate improvement in select behaviors, motor-coordination, attenuation of age-induced motor coordination decline and increased anxiety levels. | 22925203 |
| 2012-05-12 11:11:00 | findings suggest that both PDE8A and PDE8B play essential roles to maintain low cAMP levels, thereby suppressing resting steroidogenesis by keeping CEH/HSL inactive and StAR protein expression low | 22232524 |
| 2011-06-04 10:39:00 | Phosphodiesterase 8B is a major regulator of pools of cyclic AMP that promote steroidogenesis. | 21187369 |
| Type | IDs |
|---|---|
| Synonymous | B230331L10Rik, C030047E14Rik |
| Gene |
UniProtKB-ID:
E9PX38_MOUSE,
E9PXX4_MOUSE,
Q8BI47_MOUSE,
E9PYP0_MOUSE,
E9Q8J6_MOUSE
UniprotKB:
E9PX38,
E9PXX4,
Q8BI47,
E9PYP0,
E9Q8J6
UniParc:
UPI00001E7EEC,
UPI00000EB86F,
UPI0000192C2D,
UPI0001889CF0,
UPI0001889D4C
EMBL:
AC147108,
AC134439,
AC123034,
AK083166
Ensembl:
ENSMUSG00000021684
KO:
mmu:218461
|
| Nucleutide sequences |
EMBL-CDS:
BAC38791.1
Ensembl_TRS:
ENSMUST00000162153,
ENSMUST00000162412,
ENSMUST00000162292,
ENSMUST00000022192
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000124704,
ENSMUSP00000124409,
ENSMUSP00000124068,
ENSMUSP00000022192
RefSeq:
XP_006517651.1,
XP_011242953.1,
NP_001360935.1,
NP_001360933.1,
XP_036013911.1,
NP_001333711.1,
XP_030103094.1,
XP_017170983.1,
XP_011242951.1,
NP_001360934.1,
XP_011242952.1,
XP_006517657.1,
XP_017170982.1,
NP_758467.2,
XP_006517650.1,
XP_006517652.1,
XP_030103096.1,
XP_036013910.1,
XP_006517654.1,
NP_001360936.1,
NP_001164140.1,
NP_001360932.1,
XP_030103093.1,
XP_030103095.1
|
| Others |
UniRef100:
UniRef100_E9PXX4,
UniRef100_E9PYP0,
UniRef100_E9Q8J6,
UniRef100_E9PX38
UniRef90:
UniRef90_O95263-2,
UniRef90_G3TFH7,
UniRef90_E9PX38,
UniRef90_O95263-6
UniRef50:
UniRef50_O95263-6,
UniRef50_O95263-2
UniGene:
Mm.100167
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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