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21844 Tiam1

21844

Tiam1

T cell lymphoma invasion and metastasis 1

protein-coding

Mus musculus

基因描述

Type Description
Definition T cell lymphoma invasion and metastasis 1

研究结论

Date Results Publications
2020-10-31 13:15:00 Myoblast Migration and Directional Persistence Affected by Syndecan-4-Mediated Tiam-1 Expression and Distribution. 32012800
2020-08-01 11:01:00 we generated a Tiam1 mutant knock-in mouse line in which critical residues for CaMKII binding were mutated into alanines. KI mice showed reduced Rac1 activity, had smaller spines and a diminished sLTP as compared to their wild-type littermates. novel object recognition memory of these animals was impaired. We propose that the CaMKII-Tiam1 interaction regulates spine morphology in vivo and is required for memory storage. 31445077
2020-01-18 12:46:00 MiR-190a potentially ameliorates postoperative cognitive dysfunction by regulating Tiam1 31438846
2018-09-08 10:29:00 These findings highlight a regulatory pathway of Tiam1/Rac1 in Th17 cells and suggest that it may be a therapeutic target in multiple sclerosis. 27725632
2018-03-17 12:10:00 Therefore, these results suggest that Tiam1 is an important regulator of intima hyperplasia. It may regulate vascular intimal hyperplasia through the activation of Rac1. 29432743

名称对应

Type IDs
Synonymous AI847750, D16Ium10, D16Ium10e
Gene
UniProtKB-ID: E9Q1R7_MOUSE, G3UWG2_MOUSE, Q3UVX2_MOUSE, Q6P1D6_MOUSE, Q3UHH6_MOUSE
UniprotKB: E9Q1R7, G3UWG2, Q3UVX2, Q6P1D6, Q3UHH6
UniParc: UPI00005AC648, UPI000019286A, UPI000023B718, UPI0000F4BBD8, UPI00005ABD0C
EMBL: AC102908, BC065126, AC132099, AC122218, AK147392, AC087840, AK136856
Ensembl: ENSMUSG00000002489
KO: mmu:21844
Nucleutide sequences
EMBL-CDS: BAE23147.1, AAH65126.1, BAE27881.1
Ensembl_TRS: ENSMUST00000164263, ENSMUST00000163370, ENSMUST00000002588, ENSMUST00000114124
Protein sequencees
Ensembl_PRO: ENSMUSP00000126020, ENSMUSP00000132137, ENSMUSP00000002588, ENSMUSP00000109759
RefSeq: NP_001139359.1, XP_030104900.1, NP_001139358.1, NP_033410.2, XP_006523041.1, XP_006523046.1, XP_006523045.1, XP_036015765.1, XP_017172425.1, XP_006523043.1, XP_030104901.1, XP_011244414.1
Others
UniRef100: UniRef100_G3UWG2, UniRef100_Q6P1D6, UniRef100_E9Q1R7, UniRef100_Q3UVX2
UniRef90: UniRef90_Q60610, UniRef90_Q3UVX2, UniRef90_A0A2K5TZX4, UniRef90_E9Q1R7
UniRef50: UniRef50_G3MXA5, UniRef50_A0A3Q2KV74, UniRef50_Q13009
UniGene: Mm.310902

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