| Type | Description |
|---|---|
| Definition | cytotoxic granule-associated RNA binding protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:51:00 | Micellar TIA1 with folded RNA binding domains as a model for reversible stress granule formation. | 33257579 |
| 2020-04-18 12:29:00 | Overexpression of TIA1 in the ventral hippocampus inhibits fear memory in males and females. Deletion of TIA1 modulates odor avoidance behavior in female mice only. | 30865887 |
| 2020-03-28 10:58:00 | that TIA1 reduction essentially brackets the pathophysiology of tau | 30465259 |
| 2019-05-11 11:42:00 | These data provide in vivo evidence that TIA1 plays a key role in mediating toxicity and further suggest that RNA binding proteins direct the pathway of tau aggregation and the resulting neurodegeneration | 29273772 |
| 2018-12-01 10:06:00 | Results demonstrate that neither the basal nor seizure-induced expression profiles of COX-2 were altered in mice lacking a functional TIA-1 gene suggesting that TIA-1 does not contribute to regulation of COX-2 protein expression in neurons. Induced seizure threshold was also unchanged in mice lacking TIA-1 protein, indicating that this RNA binding protein does not influence the innate seizure threshold. | 29337236 |
| Type | IDs |
|---|---|
| Synonymous | 2310050N03Rik, AI256674, TIA-1, mTIA-1 |
| Gene |
UniProtKB-ID:
TIA1_MOUSE,
G5E8L2_MOUSE,
Q80ZW7_MOUSE,
Q8CII5_MOUSE,
Q564E7_MOUSE
UniprotKB:
P52912,
G5E8L2,
Q80ZW7,
Q8CII5,
Q564E7
UniParc:
UPI00000E8C5B,
UPI000154767B,
UPI000000BADB,
UPI00000041AB
EMBL:
U00689,
BC023813,
BC046812,
AC153374,
U55862,
AK088486,
AK144222
Ensembl:
ENSMUSG00000071337
KO:
mmu:21841
|
| Nucleutide sequences |
EMBL-CDS:
AAC52871.1,
AAA03711.1,
AAH46812.1,
AAH23813.1,
BAE25782.1,
BAC40385.1
Ensembl_TRS:
ENSMUST00000095753,
ENSMUST00000095752,
ENSMUST00000113713,
ENSMUST00000130967
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000093425,
ENSMUSP00000093424,
ENSMUSP00000109342,
ENSMUSP00000118558
RefSeq:
XP_036021913.1,
XP_036021909.1,
XP_006505954.1,
XP_011239587.1,
XP_036021910.1,
NP_001157550.1,
XP_006505952.1,
XP_017177002.1,
NP_001157551.1,
XP_036021911.1,
XP_030111173.1,
XP_036021912.1,
XP_017177001.1,
XP_006505956.1,
NP_035715.1
|
| Others |
UniRef100:
UniRef100_Q80ZW7,
UniRef100_G5E8L2,
UniRef100_Q8CII5,
UniRef100_P52912
UniRef90:
UniRef90_Q5PQR7,
UniRef90_P31483,
UniRef90_Q80ZW7,
UniRef90_C9JTN7
UniRef50:
UniRef50_C9JTN7,
UniRef50_Q5PQR7,
UniRef50_P31483
UniGene:
Mm.333219
CCDS:
CCDS20312.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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