| Type | Description |
|---|---|
| Definition | thyroid hormone receptor alpha |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 13:55:00 | Regulation of mitochondrial activity controls the duration of skeletal muscle regeneration in response to injury. | 31439911 |
| 2020-02-29 12:46:00 | Thra1(PV/+) mice show epithelial defects in a mouse model of resistance to thyroid hormone | 30595106 |
| 2019-08-31 12:53:00 | TRalpha seems to have an inhibitory impact on angiotensin (AGT) and AT1Ra expression, and loss of TRalpha function in TRalpha(0/0) mice increases tissue renin-angiotensin system expression in the aortic wall. More importantly, TRalpha deletion significantly increases vascular smooth muscle cells cholesterol content. Our results are consistent with a protective role of TRalpha against atherosclerosis. | 30292450 |
| 2019-08-31 10:43:00 | thyroid hormone receptor alpha deletion in ApoE-/- mice slightly increases the expression of tissue renin-angiotensin system in the aorta and aggravates the dysregulation of cholesterol content in the vascular smooth muscle cells. | 30092589 |
| 2019-01-19 11:16:00 | Knockdown of the main TR in macrophages, TRalpha, impaired polarization into proinflammatory macrophages and amplified polarization into immunomodulatory macrophages. | 29648626 |
| Type | IDs |
|---|---|
| Synonymous | 6430529J03Rik, AW259572, Erba, Nr1a1, Rvr, T3R[a], T3Ralpha, Thra1, Thra2, c-erbA-1, c-erbA-alpha, c-erbAalpha |
| Gene |
UniProtKB-ID:
THA_MOUSE
UniprotKB:
P63058
UniParc:
UPI0001BFFE46,
UPI0000004128,
UPI0001BFFE47,
UPI000000BAD2
EMBL:
CH466556,
X07751,
BC046795,
AL590963,
X51983,
X07750,
AK078233,
X07752
Ensembl:
ENSMUSG00000058756
KO:
mmu:21833
|
| Nucleutide sequences |
EMBL-CDS:
EDL16164.1,
AAH46795.1,
CAA36241.1,
CAA30575.1,
CAM46189.1,
CAA30577.1,
BAC37186.1,
CAM46188.1,
EDL16165.1,
CAM46190.1,
CAA30576.1
Ensembl_TRS:
ENSMUST00000064187,
ENSMUST00000103139
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099428,
ENSMUSP00000068281
RefSeq:
NP_001300912.1,
XP_030101776.1,
NP_835161.1
|
| Others |
UniRef100:
UniRef100_P63058
UniRef90:
UniRef90_P10827
UniRef50:
UniRef50_P10827
UniGene:
Mm.265917,
Mm.442648
CCDS:
CCDS25362.1,
CCDS83893.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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