| Type | Description |
|---|---|
| Definition | thrombospondin 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:22:00 | Mouse skin-derived precursors alleviates ultraviolet B irradiation damage via early activation of TGF-beta/Smad pathway by thrombospondin1. | 31965893 |
| 2020-12-19 13:44:00 | Myeloid-Derived TSP1 (Thrombospondin-1) Contributes to Abdominal Aortic Aneurysm Through Suppressing Tissue Inhibitor of Metalloproteinases-1. | 33028100 |
| 2020-08-22 15:30:00 | TSP1 and TSP2 deficiencies affect LOX protein distribution in the femoral diaphysis and pro-peptide removal in marrow-derived mesenchymal stem cells in vitro. | 30939949 |
| 2020-08-01 10:17:00 | Thbs1-mediated YAP activation depends on the small GTPase Rap2 and Hippo pathway and is not influenced by alteration of actin fibers. Deletion of Thbs1 in mice inhibited Thbs1/integrin beta1/YAP signaling, leading to maladaptive remodeling of the aorta in response to pressure overload and inhibition of neointima formation upon carotid artery ligation, exerting context-dependent effects on the vessel wall. | 32321834 |
| 2020-01-11 10:39:00 | We observed an upregulation in the expression of TSP1 and TSP2 mRNA in control mouse cochleae following noise exposure. afferent synaptic counts and auditory brainstem responses (ABRs) in noise-exposed TSP1 and TSP2 knockout (-/-) mice exhibited a worst recovery than controls. TSP1-/- mice showed greater susceptibility to noise-induced hearing loss at low frequencies. | 30928339 |
| Type | IDs |
|---|---|
| Synonymous | TSP-1, TSP1, Thbs-1, tbsp1 |
| Gene |
UniProtKB-ID:
Q3TR40_MOUSE,
Q80YQ1_MOUSE
UniprotKB:
Q3TR40,
Q80YQ1
UniParc:
UPI000018CE41,
UPI00005B1F21
EMBL:
BC050917,
AL845495,
AL928957,
AK163092
Ensembl:
ENSMUSG00000040152
KO:
mmu:21825
|
| Nucleutide sequences |
EMBL-CDS:
BAE37190.1,
AAH50917.1
Ensembl_TRS:
ENSMUST00000039559
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000044903
RefSeq:
NP_035710.2,
NP_001300843.1
|
| Others |
UniRef100:
UniRef100_Q80YQ1,
UniRef100_Q3TR40
UniRef90:
UniRef90_P07996
UniRef50:
UniRef50_P07996
UniGene:
Mm.4159
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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