| Type | Description |
|---|---|
| Definition | transforming growth factor, beta 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-10 12:58:00 | SMAD2 overexpression rescues the TGF-beta3 null mutant mice cleft palate by increased apoptosis. | 31677482 |
| 2019-10-19 10:21:00 | the involvement of Socs3 in Runx1-Tgfb3 signaling might explain, at least in part, the anteriorly specific downregulation of Tgfb3 expression and Stat3 activity in Runx1 mutants. This is the first study to show that the novel Runx1-Stat3-Tgfb3 axis is essential in anterior palatogenesis. | 30046048 |
| 2018-12-22 10:44:00 | The comparison of transforming growth factor beta family (TGFbeta) expression showed significantly higher levels of Tgfbeta3 transcript between nude and Balb/c mice but no differences were detected for Tgfbeta1. Nude DFs were specifically sensitive to the presence of the pro-regenerative TGFbeta3 isoform, showing increased collagen I deposition and alpha smooth muscle actin expression. | 29637306 |
| 2018-11-10 12:01:00 | Data indicated that autophagy was required for TGF-beta3 induced airway mucous hyper-production. | 29997053 |
| 2018-10-20 12:06:00 | Results suggest that the miR-140-3p is involved in osteoblast differentiation as a critical regulatory factor between Wnt3a and TGFbeta3 signaling pathways. | 29740905 |
| Type | IDs |
|---|---|
| Synonymous | TGF-beta-3, Tgfb-3 |
| Gene |
UniProtKB-ID:
Q91YU7_MOUSE,
Q3TRQ9_MOUSE
UniprotKB:
Q91YU7,
Q3TRQ9
UniParc:
UPI00005B1E99,
UPI00000E6C5E
EMBL:
AK145304,
AK132519,
AK162560,
AC134328,
BC108426,
BC014690
Ensembl:
ENSMUSG00000021253
KO:
mmu:21809
|
| Nucleutide sequences |
EMBL-CDS:
AAI08427.1,
AAH14690.1,
BAE26357.1,
BAE21215.1,
BAE36968.1
Ensembl_TRS:
ENSMUST00000003687
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000003687
RefSeq:
NP_033394.2
|
| Others |
UniRef100:
UniRef100_P17125
UniRef90:
UniRef90_P17125
UniRef50:
UniRef50_P27090
UniGene:
Mm.3992
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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