| Type | Description |
|---|---|
| Definition | transforming growth factor beta 1 induced transcript 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:21:00 | Hic-5 is required for activation of pancreatic stellate cells and development of pancreatic fibrosis in chronic pancreatitis. | 33154390 |
| 2020-10-31 13:12:00 | Alleviation of murine osteoarthritis by deletion of the focal adhesion mechanosensitive adapter, Hic-5. | 31673109 |
| 2020-06-27 11:53:00 | Results reveal novel regulation of vimentin organization/dynamics by the FA scaffold protein Hic-5 via modulation of RhoGTPases and downstream formin activity. | 31644368 |
| 2019-12-14 12:06:00 | Hic-5 plays role in orchestrating the organization of invadopodia into higher-order rosettes in fibroblasts transformed by the proto-oncogene Src. Critical Hic-5 motifs as well as phosphorylation sites that are required for the formation and dynamics of rosettes were identified. FAK kinase activity, along with its proximity to and potential interaction with the LD2,3 motifs of Hic-5, is necessary for rosette formation. | 30893012 |
| 2019-03-09 10:56:00 | High HIC5 expression is associated with tumorigenesis of colorectal cancer. | 29242607 |
| Type | IDs |
|---|---|
| Synonymous | ARA55, Hic5, TSC-5, hic-5 |
| Gene |
UniProtKB-ID:
TGFI1_MOUSE
UniprotKB:
Q62219
UniParc:
UPI00005AAF2B,
UPI00000235DB,
UPI0001E24F49,
UPI00005AAF26,
UPI000153BFD1,
UPI00005AAF2C,
UPI00005AAF29,
UPI0000F50240,
UPI00005AAF27,
UPI0001E24F48
EMBL:
DQ143894,
DQ143897,
DQ143898,
BC002049,
L22482,
DQ143891,
AK158409,
AK156423,
DQ143892,
AF083064,
BC056362,
DQ143899,
DQ143900,
DQ143895,
DQ143893,
DQ143896
Ensembl:
ENSMUSG00000030782
KO:
mmu:21804
|
| Nucleutide sequences |
EMBL-CDS:
AAZ82202.1,
AAH56362.1,
BAE34493.1,
AAZ82201.1,
AAH02049.1,
AAZ82195.1,
AAA62226.1,
AAZ82198.1,
AAZ82196.1,
AAD51090.1,
AAZ82199.1,
AAZ82203.1,
BAE33707.1,
AAZ82197.1,
AAZ82200.1,
AAZ82204.1
Ensembl_TRS:
ENSMUST00000169919,
ENSMUST00000164710,
ENSMUST00000070656,
ENSMUST00000167965
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000131705,
ENSMUSP00000068529,
ENSMUSP00000130964,
ENSMUSP00000132100
RefSeq:
NP_001276480.1,
XP_036008778.1,
XP_011240031.1,
XP_036008777.1,
NP_001276479.1,
NP_001276482.1,
XP_011240030.1,
XP_030098204.1,
NP_001276481.1
|
| Others |
UniRef100:
UniRef100_Q62219
UniRef90:
UniRef90_Q62219
UniRef50:
UniRef50_O43294
UniGene:
Mm.3248
CCDS:
CCDS21893.2,
CCDS80812.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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