| Type | Description |
|---|---|
| Definition | acyl-CoA synthetase long chain family member 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:12:00 | Metabolic reprogramming of ovarian cancer involves ACSL1-mediated metastasis stimulation through upregulated protein myristoylation. | 33082557 |
| 2020-12-26 13:14:00 | ACSL1 affects Triglyceride Levels through the PPARgamma Pathway. | 32218693 |
| 2020-08-13 18:50:00 | ACSL1 Regulates TNFalpha-Induced GM-CSF Production by Breast Cancer MDA-MB-231 Cells. | 31581558 |
| 2020-05-16 11:37:00 | We conclude that acs-13 mutations in C. elegans and ACSL1 knockdown in human cells prevent lipotoxicity by promoting increased levels of polyunsaturated fatty acid-containing phospholipids | 31769755 |
| 2020-02-15 10:46:00 | Expression of ACSL1 and Nrf2 were down-regulated in obesity-related nephropathy (ORN) patients, ob/ob mice and palmitic acid-treated HK-2 cells. Nrf2 downregulation increases reactive oxygen species production and oxidative stress. Increased oxidative stress will suppress the expression of ACSL1 ultimately leading to renal lipid deposition in renal tubulars and accelerating the development of ORN. | 31488013 |
| Type | IDs |
|---|---|
| Synonymous | ACS1, FACL1, FACL2, LACS, LACS1, LACS2 |
| Gene |
UniProtKB-ID:
ACSL1_HUMAN,
A8K9T3_HUMAN,
B7Z3Z9_HUMAN,
B4E0R0_HUMAN,
E7EPM6_HUMAN
UniprotKB:
P33121,
A8K9T3,
B7Z3Z9,
B4E0R0,
E7EPM6
UniParc:
UPI00017A8367,
UPI000023FF0A,
UPI0001AE755E,
UPI0001914C45,
UPI00016705BE,
UPI000004AC12,
UPI00015DA951
EMBL:
CH471056,
L09229,
BC026290,
AK303486,
AK296550,
D10040,
BC050073,
AK096117,
AK296826,
AK292798,
AC079257,
AC084871
Ensembl:
ENSG00000151726
KO:
hsa:2180
|
| Nucleutide sequences |
EMBL-CDS:
BAC04704.1,
AAH26290.1,
EAX04662.1,
AAH50073.1,
BAA00931.1,
BAH12438.1,
EAX04663.1,
EAX04665.1,
AAB00959.1,
BAF85487.1,
BAH12385.1,
BAG64522.1
Ensembl_TRS:
ENST00000504342,
ENST00000515030,
ENST00000513317,
ENST00000281455,
ENST00000622937,
ENST00000454703,
ENST00000507295
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000281455,
ENSP00000425006,
ENSP00000422607,
ENSP00000426150,
ENSP00000407165,
ENSP00000485264,
ENSP00000426244
RefSeq:
NP_001368807.1,
XP_016863376.1,
NP_001368809.1,
NP_001368813.1,
NP_001368810.1,
NP_001368816.1,
NP_001986.2,
NP_001368819.1,
NP_001273640.1,
NP_001368814.1,
NP_001368811.1,
NP_001273639.1,
NP_001273637.1,
NP_001368812.1,
NP_001368817.1,
NP_001368815.1,
NP_001368808.1,
NP_001368818.1,
NP_001368806.1
|
| Others |
UniRef100:
UniRef100_P33121,
UniRef100_A8K9T3,
UniRef100_B4E0R0,
UniRef100_E7EPM6
UniRef90:
UniRef90_A0A287AIP7,
UniRef90_P33121
UniRef50:
UniRef50_P18163,
UniRef50_P33121
UniGene:
Hs.406678
CCDS:
CCDS68826.1,
CCDS3839.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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