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21788 Tfpi

21788

Tfpi

tissue factor pathway inhibitor

protein-coding

Mus musculus

基因描述

Type Description
Definition tissue factor pathway inhibitor

研究结论

Date Results Publications
2020-03-07 12:15:00 Endothelial-specific TFPI deficiency promoted LPS-induced pulmonary inflammation and endothelial barrier permeability possibly via toll-like receptor 4-mediated nuclear factor kappa-light-chain-enhancer of activated B cells signaling pathway activation. 29438223
2018-05-26 11:12:00 endogenous TFPI from vascular smooth muscle cells inhibited ferric chloride-induced arterial thrombosis without causing hemostatic effects 28550640
2017-11-11 10:28:00 TFPI-1 interacts with AMOT, which led to a decrease in the phosphorylation of YAP and further increased the genes expression of the proliferation and migration involved. Our results further confirmed that atherosclerosis was a localized disease. 27875740
2016-09-24 11:58:00 Results suggest that endothelial cell-anchored TFPI controls lung tumor metastasis, and does so largely through the inhibition of local TF-induced thrombin generation and the regulation of the lung microenvironment in mice. 25945811
2016-04-09 10:38:00 Data argue against an important role for endogenous TFPI in the antibacterial, inflammatory and procoagulant response during pneumococcal pneumonia. 25832548

名称对应

Type IDs
Synonymous A630013F22Rik, AW552122, EPI, LACI
Gene
UniProtKB-ID: TFPI1_MOUSE, Q8BSB7_MOUSE
UniprotKB: O54819, Q8BSB7
UniParc: UPI00000EACF8, UPI000002B534, UPI0000003F68
EMBL: AF016313, AL845305, AK034752, AF004833, AK028356
Ensembl: ENSMUSG00000027082
KO: mmu:21788
Nucleutide sequences
EMBL-CDS: BAC25901.1, AAC40035.1, AAD01586.1, BAC28821.1
Ensembl_TRS: ENSMUST00000111718, ENSMUST00000028487, ENSMUST00000111717, ENSMUST00000090732, ENSMUST00000111714
Protein sequencees
Ensembl_PRO: ENSMUSP00000107347, ENSMUSP00000028487, ENSMUSP00000088235, ENSMUSP00000107343, ENSMUSP00000107346
RefSeq: NP_001342202.1, NP_001342200.1, XP_030105255.1, XP_006499208.1, NP_001170790.1, NP_001170791.1, XP_036016321.1, NP_035706.1, XP_006499212.1, XP_030105252.1, XP_006499213.1, XP_036016320.1
Others
UniRef100: UniRef100_Q8BSB7, UniRef100_O54819
UniRef90: UniRef90_Q8BSB7, UniRef90_O54819
UniRef50: UniRef50_Q8BSB7, UniRef50_P10646
UniGene: Mm.124316, Mm.447013
CCDS: CCDS16185.1

全选

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