| Type | Description |
|---|---|
| Definition | FA complementation group D2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:23:00 | FANCD2 knockdown with shRNA interference enhances the ionizing radiation sensitivity of nasopharyngeal carcinoma CNE-2 cells. | 32940045 |
| 2020-11-21 13:20:00 | Fanconi anemia proteins counteract the implementation of the oncogene-induced senescence program. | 31745226 |
| 2020-08-01 14:58:00 | Our study shows for the first time that FANCD2 overexpression is a strong negative prognostic factor in ovarian cancer, particularly in patients treated with TP regimen. | 30822218 |
| 2020-07-04 10:54:00 | Following introduction of genomic interstrand crosslinks and dependent on ATR and FANCD2 but not on the Fanconi anemia core proteins or FAAP24, FANCM binds the replisome complex. | 31067464 |
| 2020-06-06 11:37:00 | cryo-electron microscopy structure of the monoubiquitinated human ID complex (involving the proteins FANCI and FANCD2) bound to DNA, and reveal that it forms a closed ring that encircles the DNA | 32269332 |
| Type | IDs |
|---|---|
| Synonymous | FA-D2, FA4, FACD, FAD, FAD2, FANCD |
| Gene |
UniProtKB-ID:
FACD2_HUMAN
UniprotKB:
Q9BXW9
UniParc:
UPI000006F678,
UPI00001BD9FB,
UPI000051AE82,
UPI000006CD51
EMBL:
AF273230,
AF273244,
AF273222,
AF273233,
AF273239,
AF273229,
AF273224,
AF273237,
AF273225,
DQ341263,
AF340183,
AF273232,
AF273249,
AF273241,
AL832427,
AF273234,
AF273227,
AF230336,
AF273236,
AF273235,
BC013582,
AF273226,
AF273238,
AF273248,
AF273245,
AF273240,
AF273246,
AF273231,
AF273223,
AF273242,
AF273243,
AF273250,
AF273251,
AF273228,
AF273247,
AK022613
Ensembl:
ENSG00000144554
KO:
hsa:2177
|
| Nucleutide sequences |
EMBL-CDS:
CAH10647.1,
AAK18772.1,
AAH13582.1,
AAK18773.1,
BAB14132.1,
AAK15369.1,
ABC67466.1,
AAL05980.1
Ensembl_TRS:
ENST00000419585,
ENST00000383807,
ENST00000287647,
ENST00000431693
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000373318,
ENSP00000398754,
ENSP00000287647,
ENSP00000399354
RefSeq:
NP_001361184.1,
NP_001361182.1,
NP_149075.2,
NP_001361183.1,
NP_001018125.1,
NP_001306913.1
|
| Others |
UniRef100:
UniRef100_Q9BXW9
UniRef90:
UniRef90_Q9BXW9
UniRef50:
UniRef50_Q9BXW9
UniGene:
Hs.208388
CCDS:
CCDS2595.1,
CCDS33696.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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