| Type | Description |
|---|---|
| Definition | mannoside acetylglucosaminyltransferase 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-01-06 11:23:00 | the CD11c promoter was unexpectedly active and triggered Mgat2 deletion within multiple hematopoietic lineages, showed remarkably poor penetrance within native DC populations, and produced almost undetectable levels of green fluorescent protein signal. These findings show that the CD11c promoter is not DC-specific, and extreme care should be taken in the interpretation of data using any mouse created using the CD11c-CRE | 27146521 |
| 2017-06-03 10:23:00 | when the C-terminal cysteine (C334) was mutated, MGAT activity was actually higher than that of wild-type FL-MGAT2. Lastly, we determined that both transmembrane domains of MGAT2 are important for its ER localization, and that MGAT2 is present in mitochondrial-associated membranes. | 27373844 |
| 2017-05-13 14:52:00 | The use of 1-oleoyl-glycerol-d5 and (U13)C-TG oil followed by LC/ESI/MS/MS detection of stable-isotopic labeled DAG, TG, or glycerol provides a wide range of applications to study pathophysiological regulation of the monoacylglycerol pathway and MGAT2 activity. | 27665677 |
| 2015-02-28 11:07:00 | beneficial effects of vertical sleeve gastrectomy on body weight and glucose metabolism are independent of MGAT2 activity | 25315695 |
| 2012-11-24 10:38:00 | The results suggest that MGAT2 has a pivotal role in lipid metabolism in the small intestine, and the inhibition of MGAT2 activity may be a promising strategy for the treatment of obesity-related metabolic disorders. | 22698140 |
| Type | IDs |
|---|---|
| Synonymous | AA407964, CDGS2, GLCNACTII, GNT-II, GNT2 |
| Gene |
UniProtKB-ID:
MGAT2_MOUSE
UniprotKB:
Q921V5
UniParc:
UPI0000024142
EMBL:
BC010583,
BC027169,
AK083370,
AK152925
Ensembl:
ENSMUSG00000043998
KO:
mmu:217664
|
| Nucleutide sequences |
EMBL-CDS:
AAH27169.1,
BAC38888.1,
BAE31600.1,
AAH10583.1
Ensembl_TRS:
ENSMUST00000060579
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000057905
RefSeq:
NP_666147.1
|
| Others |
UniRef100:
UniRef100_Q921V5
UniRef90:
UniRef90_Q921V5
UniRef50:
UniRef50_Q921V5
UniGene:
Mm.206642,
Mm.398746,
Mm.483133
CCDS:
CCDS25947.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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