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21749 Terf1

21749

Terf1

telomeric repeat binding factor 1

protein-coding

Mus musculus

基因描述

Type Description
Definition telomeric repeat binding factor 1

研究结论

Date Results Publications
2021-02-13 13:24:00 Effect of exercise on telomere length and telomere proteins expression in mdx mice. 32447718
2020-10-03 12:56:00 TRF1 averts chromatin remodelling, recombination and replication dependent-break induced replication at mouse telomeres. 31934863
2020-02-15 10:15:00 Here, the authors show that Telomere Repeat Binding Factor 1 (TRF1), a component of the shelterin complex, regulates the genome-wide binding of polycomb and polycomb H3K27me3 repressive marks to pluripotency genes, thereby exerting vast epigenetic changes that contribute to the maintenance of mouse embryonic stem cells in a naive state. 31426913
2019-09-21 10:14:00 results reveal a novel mechanism of TRF1, Speedy A, and Cdk2 in protecting telomere from fusion in a highly crowded microenvironment during meiosis. 29311622
2018-06-30 10:16:00 It plays a role in hematopoietic stem cell regulation and in the maintenance of the HSC pool and the development of hematological disorders. 29550946

名称对应

Type IDs
Synonymous Pin2, Trbf1, Trf1
Gene
UniProtKB-ID: TERF1_MOUSE, Q3V252_MOUSE
UniprotKB: P70371, Q3V252
UniParc: UPI0000001AB2, UPI00001EE03C
EMBL: AK132022, AC109269, AK021235, BC034866, U65586, U70994
Ensembl: ENSMUSG00000025925
KO: mmu:21749
Nucleutide sequences
EMBL-CDS: BAB32340.1, AAB17974.1, AAH34866.1, AAB53970.1, BAE20947.1
Ensembl_TRS: ENSMUST00000188371, ENSMUST00000027057
Protein sequencees
Ensembl_PRO: ENSMUSP00000140744, ENSMUSP00000027057
RefSeq: NP_001273557.1, NP_033378.1
Others
UniRef100: UniRef100_Q3V252, UniRef100_P70371
UniRef90: UniRef90_P70371
UniRef50: UniRef50_P70371
UniGene: Mm.4306
CCDS: CCDS14827.1

全选

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研究热度

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