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217410 Trib2

217410

Trib2

tribbles pseudokinase 2

protein-coding

Mus musculus

基因描述

Type Description
Definition tribbles pseudokinase 2

研究结论

Date Results Publications
2019-11-09 11:57:00 data provide evidence for a tumour suppressor role of Trib2 in myeloid leukaemia via activation of p38 stress signalling. This newly identified role indicates that Trib2 may counteract the propagation and chemotherapy resistance of leukaemia cells. 29670085
2019-02-16 11:04:00 The expression profiles of TRIB1, TRIB2, and TRIB3 in human and murine hematopoietic stem, progenitor and mature cells, and in human leukemia datasets have been mapped. 30031847
2018-05-05 10:10:00 results suggest that Trib2 positively promotes early erythrocyte differentiation and is essential for tolerance to hemolysis. 27550848
2017-11-04 10:40:00 The absence of a change in hypocretin cell populations suggested that factors other than anti-TRIB2 antibody play a part in the loss of hypocretin neurons in narcolepsy. The increased anti-TRIB2 antibody after the destruction of hypocretin neurons suggest that anti-TRIB2 antibody in narcolepsy patients is the consequence rather than the inciting cause of hypocretin cell destruction. 28364459
2017-07-29 12:31:00 These data indicate that Trib2 has a complex role in the pathogenesis of Notch-driven T-ALL, which may vary between different T-ALL subtypes. 27191957

名称对应

Type IDs
Synonymous AW319517, TRB-2, TRB2
Gene
UniProtKB-ID: TRIB2_MOUSE
UniprotKB: Q8K4K3
UniParc: UPI0000021988
EMBL: BC037387, BC034338, BC027159, AK044747, AK144192, AF358867, AK080064, AK082329
Ensembl: ENSMUSG00000020601
KO: mmu:217410
Nucleutide sequences
EMBL-CDS: AAH27159.1, AAH37387.1, BAC38467.1, BAE25758.1, BAC32063.1, AAH34338.1, BAC37820.1, AAM45477.1
Ensembl_TRS: ENSMUST00000020922
Protein sequencees
Ensembl_PRO: ENSMUSP00000020922
RefSeq: NP_653134.2, XP_006515118.1, XP_006515117.1
Others
UniRef100: UniRef100_Q8K4K3
UniRef90: UniRef90_Q92519
UniRef50: UniRef50_Q92519
UniGene: Mm.491136
CCDS: CCDS25821.1

全选

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