| Type | Description |
|---|---|
| Definition | G protein-coupled receptor 142 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 13:00:00 | The importance of Gpr142 in the maintenance of pancreatic beta-cell function. | 30767071 |
| 2020-01-11 12:10:00 | GPR142 functions as a sensor of aromatic amino acids, controlling GIP but also CCK and GLP-1 as well as insulin and glucagon in the pancreas. | 30472415 |
| 2017-07-22 13:07:00 | these findings demonstrate GPR142 is a Tryptophan receptor critically required for insulin and incretin hormone regulation and suggest GPR142 agonists may be effective therapies that leverage amino acid sensing pathways for the treatment of type 2 diabetes. | 27322810 |
| 2010-01-21 00:00:00 | GPR142 mRNA showed a ubiquitous expression both in the brain and in various peripheral glands and organs in pre- and postnatal development. | 16378626 |
| Type | IDs |
|---|---|
| Synonymous | PGR2 |
| Gene |
UniProtKB-ID:
GP142_MOUSE,
Q1XA02_MOUSE,
A0A1C9J7L2_MOUSE,
A2AD24_MOUSE
UniprotKB:
Q7TQN9,
Q1XA02,
A0A1C9J7L2,
A2AD24
UniParc:
UPI0000D6A210,
UPI00001AA7BF,
UPI000095BF7E
EMBL:
AY288428,
KT749970,
AY957501,
AL663079,
AL669969
Ensembl:
ENSMUSG00000034677
KO:
mmu:217302
|
| Nucleutide sequences |
EMBL-CDS:
AAP72137.1,
AAY33021.1,
AOP17675.1,
CAM18758.1
Gene_ORFName:
RP23-254J18.1-001
Ensembl_TRS:
ENSMUST00000045319,
ENSMUST00000106584
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000045029,
ENSMUSP00000102194
RefSeq:
NP_001333701.1,
NP_861414.1,
NP_001366026.1
|
| Others |
UniRef100:
UniRef100_Q7TQN9,
UniRef100_Q1XA02,
UniRef100_A0A1C9J7L2
UniRef90:
UniRef90_A0A1C9J7L2,
UniRef90_Q7TQN9
UniRef50:
UniRef50_Q7TQN9
UniGene:
Mm.269127
CCDS:
CCDS25611.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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