| Type | Description |
|---|---|
| Definition | fatty acid binding protein 7 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:56:00 | Study of FABP's interactome and detecting new molecular targets in clear cell renal cell carcinoma. | 31602654 |
| 2020-09-12 11:05:00 | It sought to understand the function of fatty acid binding protein 7 (FABP7), which is expressed predominantly in Triple-negative breast cancer (TNBC) tissues. | 31484694 |
| 2020-03-07 11:54:00 | Several studies on human tumors and tumor-derived cell lines put FABP7 in the center of tumorigenesis, and its high expression level has been reported to correlate with poor prognosis in different tumor types. Several types of FABP7-expressing tumors have shown an up-regulation of cell signaling activity, but molecular mechanisms of FABP7 involvement in tumorigenesis still remain elusive. | 30245263 |
| 2020-02-01 11:34:00 | FABP7 is shown to be required for upregulation of key metastatic genes and pathways, such as integrins-Src and VEGFA, and for the growth of HER2+ breast cancer cells in the brain microenvironment in vivo. Together, these results support FABP7 as a potential target for the treatment of HER2+ Breast cancer brain metastasis. | 31324889 |
| 2019-12-21 10:51:00 | FABP7 protects astrocytes from reactive oxygen species toxicity. | 30680690 |
| Type | IDs |
|---|---|
| Synonymous | B-FABP, BLBP, FABPB, MRG |
| Gene |
UniProtKB-ID:
FABP7_HUMAN,
A0A077H155_HUMAN,
Q59HE4_HUMAN
UniprotKB:
O15540,
A0A077H155,
Q59HE4
UniParc:
UPI000013E3A9,
UPI00004F6A6C,
UPI00000735DA,
UPI0004F65013
EMBL:
CR457057,
AK311867,
U81235,
AB208815,
AK289836,
U51338,
AL645811,
KM111186,
BC012299,
AJ002962,
AL512688,
D88648,
D50373,
CH471051
Ensembl:
ENSG00000164434
KO:
hsa:2173
|
| Nucleutide sequences |
EMBL-CDS:
AAD00507.1,
AAH12299.1,
CAA05773.1,
CAC21646.1,
BAA23324.1,
AAB87141.1,
BAF82525.1,
EAW48166.1,
EAW48167.1,
BAG34808.1,
CAG33338.1,
BAA23645.1,
AIL83746.1,
BAD92052.1
Ensembl_TRS:
ENST00000356535,
ENST00000368444
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000348931,
ENSP00000357429
RefSeq:
NP_001305971.1,
NP_001437.1,
NP_001305968.1,
NP_001305970.1
|
| Others |
UniRef100:
UniRef100_A0A077H155,
UniRef100_Q59HE4,
UniRef100_O15540
UniRef90:
UniRef90_A0A2I2Z3S7,
UniRef90_O15540,
UniRef90_Q59HE4
UniRef50:
UniRef50_P51880,
UniRef50_P82188,
UniRef50_A0A3Q4H6Y6
UniGene:
Hs.26770
CCDS:
CCDS5127.1,
CCDS83121.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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