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217143 Gpr179

217143

Gpr179

G protein-coupled receptor 179

protein-coding

Mus musculus

基因描述

Type Description
Definition G protein-coupled receptor 179

研究结论

Date Results Publications
2020-01-11 10:53:00 Authors identify that major components of the extracellular matrix proteins present in the synaptic cleft-members of the heparan sulfate proteoglycan (HSPG) family-associate with the GPR158/179 group of orphan receptors. 30282023
2016-06-28 11:32:00 A no b-wave (nob) electroretinography phenotype arose spontaneously in a colony of C3H mice and was named nob5. A mutation was identified in the Gpr179 gene in homozygous nob5 mice. 26396487
2014-06-28 10:31:00 This study showed that GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells in mice. 24790204
2014-02-01 10:43:00 For most of the mutations identified so far, loss of the GPR179 protein function seems to be the underlying pathogenic mechanism leading to this form of cCSNB. 24222301
2013-12-21 11:26:00 GPR179 forms physical complexes with the main components of the metabotropic cascade, recruiting mGluR6, TRPM1, and the Regulators of G-Protein Signaling Proteins. 24114537

名称对应

Type IDs
Synonymous 5330439C02Rik, Gpr158l1
Gene
UniProtKB-ID: E9PY61_MOUSE
UniprotKB: E9PY61
UniParc: UPI000060665B
EMBL: AL596088
Ensembl: ENSMUSG00000070337
KO: mmu:217143
Nucleutide sequences
Ensembl_TRS: ENSMUST00000093942
Protein sequencees
Ensembl_PRO: ENSMUSP00000091474
RefSeq: XP_006533088.1, NP_001074689.1
Others
UniRef100: UniRef100_E9PY61
UniRef90: UniRef90_E9PY61
UniRef50: UniRef50_Q6PRD1
UniGene: Mm.32622

全选

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