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217057 Ptrh2

217057

Ptrh2

peptidyl-tRNA hydrolase 2

protein-coding

Mus musculus

基因描述

Type Description
Definition peptidyl-tRNA hydrolase 2

研究结论

Date Results Publications
2017-05-20 11:23:00 Ptrh2 levels were up-regulated in dystrophin deficient mdx muscle, which correlates with the elevated levels of the a7b1 integrin observed in mdx muscle and Duchenne muscular dystrophy patients. Similar to the a7 integrin, Ptrh2 expression was decreased in laminin-a2 null gastrocnemius muscle 28175314
2016-02-13 11:03:00 These results support an unanticipated yet essential role for Bit-1 in controlling myogenesis through regulation of Bcl-2. 25770104
2012-02-25 10:27:00 downregulation of Bit1 specifically potentiated tumor metastasis in vivo 21886829
2011-07-02 10:03:00 Bit-1 mediates integrin-dependent cell survival through activation of the NFkappaB pathway 21383007
2010-01-21 00:00:00 These studies establish the physiological significance of Bit1 activity and begin to delineate a Bit1 signaling pathway that acts through Erk regulation. 18218778

名称对应

Type IDs
Synonymous A230072I16Rik, Bit1, CGI-147, PTH 2
Gene
UniProtKB-ID: PTH2_MOUSE
UniprotKB: Q8R2Y8
UniParc: UPI00000281CF
EMBL: BC026947, AK028555, AK038888, AK031620
Ensembl: ENSMUSG00000072582
KO: mmu:217057
Nucleutide sequences
EMBL-CDS: BAC26006.1, AAH26947.1, BAC30159.1, BAC27482.1
Ensembl_TRS: ENSMUST00000108021, ENSMUST00000108022
Protein sequencees
Ensembl_PRO: ENSMUSP00000103656, ENSMUSP00000103657
RefSeq: NP_778169.1, NP_001092280.1
Others
UniRef100: UniRef100_Q8R2Y8
UniRef90: UniRef90_Q8R2Y8
UniRef50: UniRef50_Q9Y3E5
UniGene: Mm.24868
CCDS: CCDS48876.1

全选

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研究热度

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