| Type | Description |
|---|---|
| Definition | tec protein tyrosine kinase |
| Date | Results | Publications |
|---|---|---|
| 2019-05-04 13:00:00 | Inhibition of ITK and RLK attenuated psoriasis-associated signaling pathways, indicating that PRN694 is an effective psoriasis therapeutic. | 29129599 |
| 2018-03-10 10:42:00 | Results suggest that Tec kinase involves in acute inflammation process in LPS-stimulated RAW264.7 macrophages cells via NF-kappaB pathway. | 28415764 |
| 2017-09-16 11:12:00 | these data indicate that in mature B cells, Tec and Btk may compete for activation of the Akt signaling pathway, whereby the activating capacity of Btk is limited by the presence of Tec kinase. | 28275136 |
| 2016-04-23 11:57:00 | Tec enhances c-Maf-dependent IL-4 promoter activity. This effect of Tec is counteracted by Ptpn22, which physically interacts with and facilitates tyrosine dephosphorylation of c-Maf thereby attenuating its transcriptional activity. | 25993510 |
| 2015-11-07 11:49:00 | identify dectin-1 as the pathogen recognition receptor being required for Syk-dependent Tec activation. | 25474208 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
TEC_MOUSE,
Q3U436_MOUSE,
Q8CFK4_MOUSE,
Q3TH41_MOUSE
UniprotKB:
P24604,
Q3U436,
Q8CFK4,
Q3TH41
UniParc:
UPI00005B24BF,
UPI000002B507,
UPI0000020F3F,
UPI000002B508,
UPI00000270D3,
UPI00000E8FC0,
UPI000002B509,
UPI000002B50B,
UPI000002B50A
EMBL:
AF071946,
AF071938,
AF071936,
AF071940,
AK170588,
S53716,
BC037071,
AC099698,
X55663,
AK168460,
AF071943,
AF071945,
AK139329,
AF071937,
AK154457,
AF071942,
AF071939,
AC158939,
AF071944,
M33427,
AF071941
Ensembl:
ENSMUSG00000029217
KO:
mmu:21682
|
| Nucleutide sequences |
EMBL-CDS:
AAD43406.1,
AAD43405.1,
CAA39196.1,
AAA40018.1,
AAD43402.1,
AAD43407.1,
AAA13515.2,
AAD43404.1,
BAE23957.1,
BAE32599.1,
BAE41897.1,
AAH37071.1,
BAE40357.1
Ensembl_TRS:
ENSMUST00000071944,
ENSMUST00000113594,
ENSMUST00000073843
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000109224,
ENSMUSP00000071836,
ENSMUSP00000073509
RefSeq:
XP_006503911.1,
NP_001106931.1,
XP_036020885.1,
XP_011239021.1,
XP_006503910.1,
NP_001106932.1,
XP_011239020.1,
NP_001106935.1,
XP_006503909.1,
NP_038717.2,
XP_006503908.1
|
| Others |
UniRef100:
UniRef100_Q8CFK4,
UniRef100_Q3TH41,
UniRef100_P24604,
UniRef100_Q3U436
UniRef90:
UniRef90_Q3TH41,
UniRef90_Q8CFK4,
UniRef90_P42680
UniRef50:
UniRef50_P24604-4,
UniRef50_P42680
UniGene:
Mm.319581
CCDS:
CCDS51515.1,
CCDS51516.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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