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21674 Sry

21674

Sry

sex determining region of Chr Y

protein-coding

Mus musculus

基因描述

Type Description
Definition sex determining region of Chr Y

研究结论

Date Results Publications
2020-12-05 12:56:00 TET2 catalyzes active DNA demethylation of the Sry promoter and enhances its expression. 31530896
2020-11-21 13:28:00 The mouse Sry locus harbors a cryptic exon that is essential for male sex determination. 33004521
2020-05-30 13:04:00 These results suggest potential molecular causes for germ cell disruption in sex-reversed female mice, thereby providing insights into disorders of sex differentiation in humans. 30289439
2017-11-25 15:41:00 Activation of SRY and its downstream Sox9 and PDGFRalpha pathways are commonly involved in male hepatocarcinogenesis, which provides novel insights into gender disparity and sex-specific therapeutic strategies of hepatocellular carcinoma. 28942012
2017-11-04 11:56:00 MAP2K6 functions in mouse testis determination, via positive effects on Sry, and a minor role for MAP2K3. 27009039

名称对应

Type IDs
Synonymous Tdf, Tdy
Gene
UniProtKB-ID: SRY_MOUSE, Q53WV7_MOUSE
UniprotKB: Q05738, Q53WV7
UniParc: UPI00000005EF
EMBL: U70655, U70656, U03645, X67204, X55491
Ensembl: ENSMUSG00000069036
KO: mmu:21674
Nucleutide sequences
EMBL-CDS: CAB56798.1, AAB60446.1, CAA39111.1, AAC53445.1, AAC53446.1
Ensembl_TRS: ENSMUST00000091178
Protein sequencees
Ensembl_PRO: ENSMUSP00000088717
RefSeq: NP_035694.1
Others
UniRef100: UniRef100_Q05738
UniRef90: UniRef90_Q05738
UniRef50: UniRef50_Q05738
UniGene: Mm.377114
CCDS: CCDS30545.1

全选

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研究热度

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