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216456 Gls2

216456

Gls2

glutaminase 2 (liver, mitochondrial)

protein-coding

Mus musculus

基因描述

Type Description
Definition glutaminase 2 (liver, mitochondrial)

研究结论

Date Results Publications
2018-11-03 10:38:00 Data (including data from studies in knockout/transgenic mice) suggest Ppp2ca supports cortical neuronal growth and cognitive function via regulating p73/Gls2 signal transduction in neurons of hippocampus. Ppp2ca gene knock-out results in embryonic cortical atrophy with learning/memory deficits. (Ppp2ca = protein phosphatase 2a catalytic subunit alpha isoform; p73 = transformation related protein 73; Gls2 = glutaminase-2) 29274472
2017-07-01 11:14:00 Gls2 expression is regulated by the dietary protein/carbohydrate ratio. This effect was not observed in Ppara-null mice. 27466601
2012-10-06 11:35:00 Study demonstrated expression of alternative transcripts of the mammalian Gls2 gene. Transcriptional mechanisms giving rise to GLS2 variants and isolation of novel GLS2 transcripts in human, rat and mouse are presented. 22679499
2010-05-31 11:23:00 Phosphate-activated glutaminase (GLS2) is a p53-inducible regulator of glutamine metabolism and reactive oxygen species 20351271

名称对应

Type IDs
Synonymous A330074B06Rik, AI195532, GA, GLS, Lga
Gene
UniProtKB-ID: GLSL_MOUSE
UniprotKB: Q571F8
UniParc: UPI0000025E22
EMBL: BC141115, AK165896, AK220231
Ensembl: ENSMUSG00000044005
KO: mmu:216456
Nucleutide sequences
EMBL-CDS: BAE38445.1, AAI41116.1, BAD90156.1
Ensembl_TRS: ENSMUST00000044776
Protein sequencees
Ensembl_PRO: ENSMUSP00000047376
RefSeq: NP_001272708.1, NP_001272706.1, NP_001028436.2
Others
UniRef100: UniRef100_Q571F8
UniRef90: UniRef90_Q571F8
UniRef50: UniRef50_Q9UI32
UniGene: Mm.30102, Mm.447148
CCDS: CCDS24263.1

全选

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研究热度

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