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2160 F11

2160

F11

coagulation factor XI

protein-coding

Homo sapiens

基因描述

Type Description
Definition coagulation factor XI

研究结论

Date Results Publications
2020-09-12 16:04:00 Hydrogen-deuterium exchange mass spectrometry highlights conformational changes induced by factor XI activation and binding of factor IX to factor XIa. 31519061
2020-08-01 12:50:00 Our study showed that even when family members have the same germline F11 variant, they still may experience phenotypic variability, making disease prognosis more complex. 32118380
2020-07-11 12:30:00 Low factor XI was associated with reduced risk of recurrent venous thrombosis 30784172
2020-07-11 10:22:00 kallikrein has an apple domain disc with a rotated conformation compared to factor XI 30801944
2020-06-27 11:53:00 The compound heterozygous c.738G>A (p.Trp228stop) and c.938G>T (p.Ser295Ile) variants of the F11 gene probably underlie the decreased FXI level in this hereditary coagulation factor XI deficiency pedigree 32335872

名称对应

Type IDs
Synonymous FXI, PTA
Gene
UniProtKB-ID: FA11_HUMAN
UniprotKB: P03951
UniParc: UPI000002A94F, UPI000000D8B7
EMBL: M18299, M20218, M18301, BC119014, M18296, M18300, M18304, BC122863, CH471056, M18303, AF045649, M13142, AY191837, M18302, M19417, M20217, M21184, M18298, AC110771
Ensembl: ENSG00000088926
KO: hsa:2160
Nucleutide sequences
EMBL-CDS: EAX04621.1, AAC24506.1, AAA52487.1, AAI22864.1, AAA51985.1, AAY40901.1, AAI19015.1, AAN85554.1
Ensembl_TRS: ENST00000403665, ENST00000264692
Protein sequencees
Ensembl_PRO: ENSP00000384957, ENSP00000264692
RefSeq: XP_006714200.1, XP_005262880.1, XP_016863374.1, NP_000119.1, XP_005262879.1, XP_016863373.1, XP_005262878.1, XP_016863375.1, NP_001341733.1
Others
UniRef100: UniRef100_P03951
UniRef90: UniRef90_P03951
UniRef50: UniRef50_P03951
UniGene: Hs.1430
CCDS: CCDS3847.1

全选

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