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215798 Adgrg6

215798

Adgrg6

adhesion G protein-coupled receptor G6

protein-coding

Mus musculus

基因描述

Type Description
Definition adhesion G protein-coupled receptor G6

研究结论

Date Results Publications
2020-02-01 10:46:00 These findings establish ADGRG6 and as novel regulators of intervertebral disc endplate and growth plate integrity in the mouse, and implicate signaling as promising therapeutic targets for endplate-oriented disc degeneration 31652254
2017-07-29 11:19:00 we show that the adhesion class G protein-coupled receptor (GPCR) Gpr126/Adgrg6 is required for remyelination, macrophage recruitment, and axon regeneration following nerve 27927955
2016-10-01 12:25:00 PrP(C) promotes myelin homeostasis through flexible tail-mediated Gpr126 agonism 27501152
2016-05-21 11:04:00 Together, these data uncover Gpr126 as a genetic cause for the pathogenesis of Adolescent idiopathic scoliosis (AIS) and pectus excavatum in a mouse model. 25954032
2015-02-14 11:44:00 GPR126 modulates both physiological and pathological angiogenesis through VEGF signaling 25217645

名称对应

Type IDs
Synonymous 1190004A11Rik, AI449247, AW045736, DREG, Gm222, Gpr126
Gene
UniProtKB-ID: AGRG6_MOUSE
UniprotKB: Q6F3F9
UniParc: UPI00001A418A
EMBL: BC046534, AB183545
Ensembl: ENSMUSG00000039116
KO: mmu:215798
Nucleutide sequences
EMBL-CDS: AAH46534.1, BAD27570.1
Ensembl_TRS: ENSMUST00000041168
Protein sequencees
Ensembl_PRO: ENSMUSP00000043055
RefSeq: XP_006512743.1, XP_030100861.1, XP_006512744.1, NP_001002268.1, XP_006512745.1, XP_006512741.1, XP_036011624.1, XP_006512742.1, XP_017169370.1
Others
UniRef100: UniRef100_Q6F3F9
UniRef90: UniRef90_Q6F3F9
UniRef50: UniRef50_Q86SQ4
UniGene: Mm.440142
CCDS: CCDS35848.1

全选

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研究热度

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