| Type | Description |
|---|---|
| Definition | ectonucleoside triphosphate diphosphohydrolase 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-02-10 10:50:00 | NTPDase2 and -3 are ecto-enzymes expressed in the enteric nervous system. Both enzymes confer protection against gut inflammation in experimental colitis and exhibit alterations in Crohn's disease. These observations suggest that purinergic signalling modulated by E-NTPDases governs neuro-immune interactions that are relevant in Crohn's disease. | 28472257 |
| 2017-06-24 10:31:00 | Results identified the expression of ecto-NTPDase3 in trigeminal nociceptive neurons and demonstrated the presence of functional ecto-ATPase activity in trigeminal nerves and established that ecto-NTPDase3mediates extracellularATP degradation in the nociceptive lamina on the brainstem. | 27706204 |
| 2017-06-10 11:18:00 | Mesenteric endothelial cells are primed by schistosomiasis to a pro-inflammatory phenotype characterized by an increased expression of NTPDases 2 and 3, favoring ADP accumulation and mononuclear cell adhesion, possibly contributing to mesenteric inflammation and schistosomiasis morbidity via P2Y1 receptor signaling. | 26924460 |
| 2015-06-20 11:28:00 | In bladder cancer disease progression there was a weak immunostaining to NTPDase in bladder samples. | 24464643 |
| 2014-01-25 11:10:00 | NTPDase3 is the major ectonucleotidase in pancreatic beta-cells in multiple species and modulates insulin secretion by controlling activation of purinergic receptors. | 24085034 |
| Type | IDs |
|---|---|
| Synonymous | Cd39l3, HB6, NTPDase-3 |
| Gene |
UniProtKB-ID:
Q8BFW6_MOUSE
UniprotKB:
Q8BFW6
UniParc:
UPI00000EBA98
EMBL:
BC079871,
AY376710,
AC137127,
AY714060,
AK087561,
AK046218,
AC123708
Ensembl:
ENSMUSG00000041608
KO:
mmu:215446
|
| Nucleutide sequences |
EMBL-CDS:
AAQ86585.1,
BAC39928.1,
AAH79871.1,
AAU13839.1,
BAC32641.1
Ensembl_TRS:
ENSMUST00000047687
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000036830
RefSeq:
NP_848791.3,
XP_036010724.1
|
| Others |
UniRef100:
UniRef100_Q8BFW6
UniRef90:
UniRef90_Q8BFW6
UniRef50:
UniRef50_O75355-2
UniGene:
Mm.76648
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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