| Type | Description |
|---|---|
| Definition | SUMO/sentrin specific peptidase 6 |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 10:22:00 | postnatal loss of the desumoylase SUMO1/sentrin-specific peptidase 6 (SENP6) causes premature aging. OCP-specific SENP6 knockout mice exhibit smaller skeletons, with elevated apoptosis and cell senescence in OCPs and chondrocytes. SENP6 interacts with, desumoylates, and stabilizes TRIM28, suppressing p53 activity. | 29321472 |
| 2014-01-18 12:01:00 | Negative regulation of TLR inflammatory signaling by the SUMO-deconjugating enzyme SENP6. | 23825957 |
| Type | IDs |
|---|---|
| Synonymous | 2810017C20Rik, E130319N12Rik, Susp1, mKIAA0797 |
| Gene |
UniProtKB-ID:
SENP6_MOUSE,
F6Z9A1_MOUSE
UniprotKB:
Q6P7W0,
F6Z9A1
UniParc:
UPI0001F78A76,
UPI00001F7B6F,
UPI00002190FA
EMBL:
AC142111,
AK129219,
AK053904,
AK083377,
BC061480
Ensembl:
ENSMUSG00000034252
KO:
mmu:215351
|
| Nucleutide sequences |
EMBL-CDS:
BAC38892.2,
AAH61480.1,
BAC98029.1,
BAC35583.1
Ensembl_TRS:
ENSMUST00000037484,
ENSMUST00000164859,
ENSMUST00000165607
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000047220,
ENSMUSP00000128918,
ENSMUSP00000126777
RefSeq:
XP_006511080.1,
XP_036010719.1,
XP_036010720.1,
XP_030100089.1,
XP_030100090.1,
XP_006511077.1,
NP_001298039.1,
XP_036010721.1,
NP_666115.2,
XP_036010723.1,
XP_036010722.1,
XP_006511078.1,
XP_006511079.1,
XP_036010718.1
|
| Others |
UniRef100:
UniRef100_Q6P7W0,
UniRef100_F6Z9A1
UniRef90:
UniRef90_Q6P7W0
UniRef50:
UniRef50_Q9GZR1
UniGene:
Mm.28232
CCDS:
CCDS40705.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32325033 |
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili |
2020-04-22 | - |
| 29321472 |
Desumoylase SENP6 maintains osteochondroprogenitor homeostasis by suppressing the p53 pathway. Nat Commun Jianshuang Li , Di Lu , Hong Dou , Huadie Liu , Kevin Weaver , Wenjun Wang , Jiada Li , Edward T H Yeh , Bart O Williams , Ling Zheng , Tao Yang |
2018-01-10 | - |
| 23825957 |
Negative regulation of TLR inflammatory signaling by the SUMO-deconjugating enzyme SENP6. PLoS Pathog. Xing Liu , Wei Chen , Qiang Wang , Li Li , Chen Wang |
2013-01-01 |
Ikbkb,
Ikbkg,
Sumo3,
Senp6,
Cyld
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
| 18799693 |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin |
2008-10-01 |
Gm11335,
Gm17762,
A930017K11Rik,
BC028777,
Gm13999,
Gm11696,
Gm12359,
Gm10589,
D030047H15Rik,
Gm10856,
Gm10685,
Gm10062,
Gm10433,
Gm10648,
Gm10840,
Gm15441,
Gm10684,
Gm9900,
Gm10822,
Gm10687,
Gm11744,
Gm10747,
Arih2os,
B230344G16Rik,
Fmr1os,
Tmem51os1,
Gm14488,
Gm13033,
Gm10789,
Gm10615,
Gm1976,
Gm9967,
Gm9917,
Gm1974,
Gm11496,
Gm13580,
Gm2085,
Gm2183,
Gm2245,
Tbx3os1,
Gm12980,
Gm2329,
Lncenc1,
Gm2381,
Snhg12,
Gm2479,
Gm12942,
Gm2529,
Gm2533,
Rpl30-ps7,
Rsf1os2,
Gm2695,
2810416G20Rik,
Rpl30-ps6,
Gm2773,
Gm2788,
Dynlt1f,
Gm9793,
Gm2885,
Gm2920,
Gm15506,
Gm11627,
Gm10518,
Gm13496,
Gm3134,
Gm12827,
Gm3143,
Gm10144,
Ahnak2,
Gm3196,
Gm13242,
Gm3325,
Gm13247,
Gm10863,
Gm13157,
4930522L14Rik,
Gm3552,
Gm15226,
Gm3604,
Gm3643,
BC005561,
Gm3716,
2810410L24Rik,
Gm10282,
Gm3839,
Nhsl2,
4732419C18Rik,
Gm3906,
Gm3973,
Gm4013,
Apol7d,
Gm12057,
Gm10489,
Rex2,
1110002L01Rik,
Gm4189,
Gm4204,
4632428C04Rik,
9130023H24Rik
|
| 18973680 |
BMC Genomics Owen J Tamplin , Doris Kinzel , Brian J Cox , Christine E Bell , Janet Rossant , Heiko Lickert |
2008-01-01 |
Rnaset2a,
Ildr2,
2810410L24Rik,
Pifo,
Trrap,
Plekha1,
Cd276,
Phldb1,
6330403K07Rik,
Txndc5,
Unc119b,
Otub1,
Napg,
Cald1,
Pygb,
Pygl,
Hspa13,
Rpl31,
Acvr2b,
Agtrap,
Ank3,
Anxa5,
Ap4s1,
App,
Arg1,
Astn1,
Atm,
Bcl2l2,
Fabp7,
Hyou1,
Pdia4,
Cbx3,
Cd24a,
Cd59a,
Cdkn1c,
Cdx1,
Cldn4,
Cnn2,
Col1a1,
Hapln1,
Csnk2a1,
Cyb561,
Cyp51,
Dbt,
Mapre1,
Esd,
Amz2,
Colec12,
Fgfr2,
Fjx1,
Foxd4,
Flt4,
Fstl1,
Gal,
Galnt1,
Galt,
Gas5,
Nr6a1,
Gna14,
Gng10,
Gpc3,
Lpar1,
Gpx2,
Gsta4,
Gstm5,
Hdgf,
Hmgb1,
Foxa1,
Foxa2,
Hnrnpab,
Hoxa1,
Hpn,
Prmt1,
Sdc2,
Igfbp3,
Igfbp5,
Inpp1,
Itch,
Itga3,
Stt3a,
Khsrp,
Mxd3,
Cd99l2,
Mfap2,
Mdk,
Meis1,
Mest,
Kitl,
Mlf1,
Mvk,
Myef2,
Myl4,
Myl7,
Myl1,
Nnat,
Pabpc1,
Pak1,
Pcolce,
Pcsk5
|
| 16141073 |
Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G Engström , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium |
2005-09-02 |
Gm14018,
Gm14964,
F630206G17Rik,
Oog3,
Notumos,
Ldlrap1,
Mdn1,
Pydc3,
9330171B17Rik,
Mfap1b,
Tmsb15b2,
Gm12802,
E430020m11rik,
Gm11335,
Gm15772,
Gm17762,
A930017K11Rik,
LOC100036513,
Gata5os,
Umad1,
Gm16982,
Gm9887,
Gm9872,
LOC100036530,
Gm9934,
Gm9913,
Gm11149,
BC028777,
Gm13999,
LOC100036540,
Gm9744,
Gm9983,
D630002J18Rik,
Gm16525,
Gm11696,
Dnajc3,
9430060I03Rik,
Gm12359,
4921516A02Rik,
Fam129c,
Gm10589,
Rsph3b,
Rnaset2a,
5430403G19Rik,
D030047H15Rik,
Gm13274,
B930046K06Rik,
Gm10862,
Gm10792,
Gm10802,
Gm10532,
G730003C15Rik,
Runx2os1,
Gm15612,
Gm10856,
Gm10857,
Gm10685,
Gm10803,
Gm10723,
F630028O10Rik,
Gm10836,
Gm10405,
Gm10513,
Gm10609,
F630201L12Rik,
4932427H20Rik,
Zfp389,
Gm10763,
Gm10062,
Gm10714,
Gm10531,
Gm10876,
Gm10750,
Gm10433,
Gm10837,
Gm10647,
Gm10648,
Gm10650,
Gm10610,
F830115B05Rik,
Gm10473,
Gm10614,
Gm10286,
G730046D07Rik,
Gm10287,
Gm10785,
Gm10183,
Gm10512,
1700061E17Rik,
Gm44113,
Gm10579,
Gm10741,
Gm10827,
Gm10522,
Gm10536,
Gm15998,
Faddos,
D130050E23Rik,
Gm10735
|
| 16141072 |
The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C Schönbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) |
2005-09-02 | - |
| 15782199 |
Nat. Methods Akira Watahiki , Kazunori Waki , Norihito Hayatsu , Toshiyuki Shiraki , Shinji Kondo , Mari Nakamura , Daisuke Sasaki , Takahiro Arakawa , Jun Kawai , Matthias Harbers , Yoshihide Hayashizaki , Piero Carninci |
2004-12-01 |
Ldlrap1,
Mfap1b,
Dnajc3,
Fam129c,
Rsph3b,
Rnaset2a,
Fam174b,
Gm9797,
Gm2296,
Gm15429,
Atp6v0c-ps2,
Kcnj13,
Gm10291,
Gm15264,
Rpl3-ps1,
Gm4482,
Srcap,
Tpt1-ps3,
Rps2-ps6,
Orai2-ps,
Tdrd7,
Sco2,
Pafah2,
Akna,
H6pd,
Stx12,
Gm15590,
Osbpl9,
AU040320,
Ppp1r8,
Bsdc1,
Gm37013,
Slc44a1,
Zfand2a,
Rpl5,
LOC100503956,
Atg14,
Rell1,
Slc15a4,
Noc4l,
Psph,
9330133O14Rik,
Mapre3,
Usp30,
Ube3c,
Rita1,
Tbc1d14,
Gm21685,
Chpf2,
Tyw1,
Rab28,
Zfp513,
LOC101055802,
Zfp282,
Snx21,
Rpusd3,
Itfg2,
Pot1a,
Tada3,
Brk1,
Eogt,
Dhx32,
Ric8a,
Inpp5f,
Plekhg2,
Hsd3b7,
Mob2,
Prkd2,
Vrk3,
Grwd1,
Pwwp2b,
Spty2d1,
Faap24,
Ints4,
Rrp8,
Unc45a,
Sf3b3,
D8Ertd738e,
Usb1,
Smim19,
Dohh,
Fam192a,
Enkd1,
Prmt9,
Zdhhc7,
Snapc2,
Gpat4,
Ankrd10,
Cog4,
Clk3,
Xylb,
Imp3,
Cmtm7,
Ano10,
Alg9,
Plekho2,
Mapkapk3,
Acad11,
Gm30491
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
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目前还没有研究热点人员