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215351 Senp6

215351

Senp6

SUMO/sentrin specific peptidase 6

protein-coding

Mus musculus

基因描述

Type Description
Definition SUMO/sentrin specific peptidase 6

研究结论

Date Results Publications
2018-12-22 10:22:00 postnatal loss of the desumoylase SUMO1/sentrin-specific peptidase 6 (SENP6) causes premature aging. OCP-specific SENP6 knockout mice exhibit smaller skeletons, with elevated apoptosis and cell senescence in OCPs and chondrocytes. SENP6 interacts with, desumoylates, and stabilizes TRIM28, suppressing p53 activity. 29321472
2014-01-18 12:01:00 Negative regulation of TLR inflammatory signaling by the SUMO-deconjugating enzyme SENP6. 23825957

名称对应

Type IDs
Synonymous 2810017C20Rik, E130319N12Rik, Susp1, mKIAA0797
Gene
UniProtKB-ID: SENP6_MOUSE, F6Z9A1_MOUSE
UniprotKB: Q6P7W0, F6Z9A1
UniParc: UPI0001F78A76, UPI00001F7B6F, UPI00002190FA
EMBL: AC142111, AK129219, AK053904, AK083377, BC061480
Ensembl: ENSMUSG00000034252
KO: mmu:215351
Nucleutide sequences
EMBL-CDS: BAC38892.2, AAH61480.1, BAC98029.1, BAC35583.1
Ensembl_TRS: ENSMUST00000037484, ENSMUST00000164859, ENSMUST00000165607
Protein sequencees
Ensembl_PRO: ENSMUSP00000047220, ENSMUSP00000128918, ENSMUSP00000126777
RefSeq: XP_006511080.1, XP_036010719.1, XP_036010720.1, XP_030100089.1, XP_030100090.1, XP_006511077.1, NP_001298039.1, XP_036010721.1, NP_666115.2, XP_036010723.1, XP_036010722.1, XP_006511078.1, XP_006511079.1, XP_036010718.1
Others
UniRef100: UniRef100_Q6P7W0, UniRef100_F6Z9A1
UniRef90: UniRef90_Q6P7W0
UniRef50: UniRef50_Q9GZR1
UniGene: Mm.28232
CCDS: CCDS40705.1

全选

研究热度
发表文献
热点单位
排名 科研单位 文献
1

Yokohama Institute

1
2

RIKEN Yokohama Institute 1-7-22 Suehiro-cho

1
3

RIKEN Yokohama Institute

1
4

Genome Science Laboratory, RIKEN, Wako main campus, 2-1 Hirosawa, Wako, Saitama, 351-0198 Japan.

1
5

Central South University

1
热点人员
排名 研究人员 文献
1

P Carninci

7
2

Y Hayashizaki

6
3

K Shibata

5
4

M Itoh

5
5

H Konno

5
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