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2151 F2RL2

2151

F2RL2

coagulation factor II thrombin receptor like 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition coagulation factor II thrombin receptor like 2

研究结论

Date Results Publications
2016-11-12 10:23:00 PAR3 is essential in thrombin stimulated insulin secretion. 26742564
2016-08-06 11:59:00 TFRGAP, a PAR-3 mimicking peptide significantly induced the phosphorylation of eNOS-Thr-495 with minimal phosphorylation of eNOS-Ser-1177 with no change in nitric oxide production. 26729042
2015-02-28 12:17:00 These data provide intriguing novel insights into the diversification of functional selectivity of protease signaling achievable by canonical and noncanonical PAR activation, such as the activation of vascular-protective Tie2 by noncanonical PAR3 activation. 25320242
2015-01-31 11:12:00 In pancreatic adenocarcinoma cells, PAR3 knockdown enhances cell adhesion. We propose this is due to increased expression of E-cadherin, leading to a greater adhesion of free-floating cells to cells bound to the surface via integrins, particularly ITGalphav. 24699825
2014-08-16 12:30:00 Data indicate that knockdowns of all three PARs PAR-1, PAR-2, and PAR-3 exhibited changes in the expression of CDC42, which correlated with the changes in their invasion. 23921961

名称对应

Type IDs
Synonymous PAR-3, PAR3
Gene
UniProtKB-ID: PAR3_HUMAN
UniprotKB: O00254
UniParc: UPI00017A7898, UPI0000050431
EMBL: BC093648, AC026725, CH471084, AK298585, AK312848, U92971, BX537386, BC093650, AF374726
Ensembl: ENSG00000164220
KO: hsa:2151
Nucleutide sequences
EMBL-CDS: BAG60775.1, AAC51218.1, CAD97628.1, EAW95778.1, AAH93650.1, BAG35701.1, AAK51564.1, AAH93648.1
Ensembl_TRS: ENST00000296641, ENST00000504899
Protein sequencees
Ensembl_PRO: ENSP00000426703, ENSP00000296641
RefSeq: NP_001243495.1, NP_004092.1
Others
UniRef100: UniRef100_O00254
UniRef90: UniRef90_O00254
UniRef50: UniRef50_O00254
UniGene: Hs.42502
CCDS: CCDS4031.1, CCDS58959.1

全选

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研究热度

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