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215095 Astl

215095

Astl

astacin-like metalloendopeptidase (M12 family)

protein-coding

Mus musculus

基因描述

Type Description
Definition astacin-like metalloendopeptidase (M12 family)

研究结论

Date Results Publications
2018-05-19 10:28:00 Intracellular activation of Astl mediates pre-fertilization hardening of the zona pellucida. 28911209
2017-05-27 11:34:00 Seven amino acid motif near Astl N-terminus is necessary and sufficient for cortical granule localization. 28114310
2012-07-21 11:25:00 ASTL is dynamically expressed in the embryonic epithelium and in embryonic stem cells, suggesting an important function for the control of epithelial cell behavior during early development. 22275110
2012-06-09 11:23:00 Ovastacin is a pioneer component of mouse cortical granules and plays a definitive role in the postfertilization block to sperm binding that ensures monospermic fertilization and successful development 22472438
2012-05-26 10:23:00 Data show that SAS1B/SAS1R (Sperm Acrosomal SLLP1 Binding/Sperm Acrosomal SLLP1 receptor) bound to sperm acrosomal protein SlLP1 with high affinity. 22206759

名称对应

Type IDs
Synonymous 7420700F21, C87576, Sas1b
Gene
UniProtKB-ID: ASTL_MOUSE
UniprotKB: Q6HA09
UniParc: UPI0001A66AC7, UPI0000356120, UPI000231DFE5, UPI0000026FAE, UPI00003B0CCA, UPI000231DFE4
EMBL: AK033037, AL731836, AL845368, FJ187795, FJ187792, FJ187794, FJ187793, FJ187791, FJ187790, BC064729, AJ537599
Ensembl: ENSMUSG00000050468
KO: mmu:215095
Nucleutide sequences
EMBL-CDS: ACN71160.1, ACN71161.1, ACN71163.1, ACN71162.1, CAD61264.2, AAH64729.2, ACN71164.1, BAC28134.1, ACN71165.1
Ensembl_TRS: ENSMUST00000179618, ENSMUST00000089673, ENSMUST00000059839
Protein sequencees
Ensembl_PRO: ENSMUSP00000054456, ENSMUSP00000087102, ENSMUSP00000135987
RefSeq: NP_766127.1, NP_001277932.1
Others
UniRef100: UniRef100_Q6HA09
UniRef90: UniRef90_Q6HA09
UniRef50: UniRef50_Q6HA09
UniGene: Mm.31313, Mm.58214
CCDS: CCDS16700.1, CCDS71138.1

全选

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