| Type | Description |
|---|---|
| Definition | lysine (K)-specific demethylase 5A |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:34:00 | KDM5A mutations identified in autism spectrum disorder using forward genetics. | 33350388 |
| 2020-02-29 11:29:00 | C/EBPbeta knockdown impaired the recruitment of KDM5A to the Wnt6 promoter | 31061100 |
| 2019-11-23 10:29:00 | Our results uncover a regulatory mechanism in which HDAC1 negatively regulates RBPJ binding on mitotic chromatin in a KDM5A-dependent manner. We propose that relative chromatin affinity of a minimal regulatory complex, reflecting a specific transcription program, renders selective RBPJ binding on mitotic chromatin. | 30916347 |
| 2018-09-01 11:20:00 | Conditional, systemic ablation of RBP2 in pituitary or thyroid tumor-bearing Rb1(+/-) mice is sufficient to slow tumor growth and significantly extend survival without causing obvious toxicity to the host. These findings show that established Rb1-null tumors require RBP2 for growth. | 29610306 |
| 2017-10-14 12:08:00 | KDM5A-mediated H3K4me3 modification participated in the etiology of osteoporosis and may provide new strategies to improve the clinical efficacy of BMP2 in osteoporotic conditions. | 27512956 |
| Type | IDs |
|---|---|
| Synonymous | AA409370, C76986, Jarid1a, RBP2, Rbbp2 |
| Gene |
UniProtKB-ID:
KDM5A_MOUSE
UniprotKB:
Q3UXZ9
UniParc:
UPI0000605397
EMBL:
AK135085,
AC155720,
AK166055,
BC080691,
AK144877,
AC078896
Ensembl:
ENSMUSG00000030180
KO:
mmu:214899
|
| Nucleutide sequences |
EMBL-CDS:
BAE26113.1,
BAE38548.1,
AAH80691.1,
BAE22414.1
Ensembl_TRS:
ENSMUST00000005108
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000005108
RefSeq:
XP_011239583.1,
NP_666109.2
|
| Others |
UniRef100:
UniRef100_Q3UXZ9
UniRef90:
UniRef90_P29375
UniRef50:
UniRef50_P29375
UniGene:
Mm.404761,
Mm.463658
CCDS:
CCDS51889.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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